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Biomea Fusion
BMEA

87 hedge funds and large institutions have $51.7M invested in Biomea Fusion in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 22 increasing their positions, 24 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

143% more call options, than puts

Call options by funds: $2.77M | Put options by funds: $1.14M

17.38% more ownership

Funds ownership: 59.11% → 76.49% (+17%)

10% more capital invested

Capital invested by funds: $47.2M → $51.7M (+$4.55M)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

8% less repeat investments, than reductions

Existing positions increased: 22 | Existing positions reduced: 24

8% less funds holding

Funds holding: 95 → 87 (-8)

22% less first-time investments, than exits

New positions opened: 29 | Existing positions closed: 37

Holders
87
Holders Change
-8
Holders Change %
-8.42%
% of All Funds
1.15%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
29
Increased
22
Reduced
24
Closed
37
Calls
$2.77M
Puts
$1.14M
Net Calls
+$1.63M
Net Calls Change
+$1.93M

Top Buyers

Rank Fund Capital Flow
1
HCM
Heights Capital Management
California
+$7.4M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$3.48M
3
WP
Woodline Partners
California
+$2.9M
4
BOCH
Blue Owl Capital Holdings
New York
+$2.5M
5
ACM
Aisling Capital Management
New York
+$2.41M

Top Sellers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
-$2.71M
2
N
Nuveen
North Carolina
-$2.13M
3
State Street
State Street
Massachusetts
-$957K
4
Geode Capital Management
Geode Capital Management
Massachusetts
-$678K
5
Renaissance Technologies
Renaissance Technologies
New York
-$592K
Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$13M +$3.48M +1,808,109 +33%
HCM
2
Heights Capital Management
California
$6.91M +$7.4M +3,839,349 New
CAM
3
Cormorant Asset Management
Massachusetts
$6.43M – – –
ACM
4
Aisling Capital Management
New York
$3.69M +$2.41M +1,250,000 +156%
Vanguard Group
5
Vanguard Group
Pennsylvania
$3.38M +$966K +501,626 +36%
WP
6
Woodline Partners
California
$3.14M +$2.9M +1,502,990 +624%
BOCH
7
Blue Owl Capital Holdings
New York
$2.34M +$2.5M +1,300,000 New
BlackRock
8
BlackRock
New York
$1.36M -$2.71M -1,406,440 -65%
Federated Hermes
9
Federated Hermes
Pennsylvania
$1.04M -$34.2K -17,757 -3%
Adage Capital Partners
10
Adage Capital Partners
Massachusetts
$900K – – –
Millennium Management
11
Millennium Management
New York
$839K +$355K +184,219 +65%
Morgan Stanley
12
Morgan Stanley
New York
$696K -$180K -93,556 -19%
BGM
13
Burkehill Global Management
New York
$630K +$674K +350,000 New
Two Sigma Investments
14
Two Sigma Investments
New York
$629K -$236K -122,712 -26%
AQR Capital Management
15
AQR Capital Management
Connecticut
$609K +$143K +74,318 +28%
Two Sigma Advisers
16
Two Sigma Advisers
New York
$534K -$374K -194,200 -40%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$493K -$678K -352,131 -56%
SC
18
Scotia Capital
Ontario, Canada
$459K +$491K +255,000 New
SCM
19
Superstring Capital Management
New York
$450K +$482K +250,000 New
UBS Group
20
UBS Group
Switzerland
$446K +$20.8K +10,787 +5%
Goldman Sachs
21
Goldman Sachs
New York
$355K +$182K +94,606 +92%
Janus Henderson Group
22
Janus Henderson Group
United Kingdom
$272K +$290K +150,761 New
XT
23
XTX Topco
Cayman Islands
$270K +$289K +149,779 New
National Bank of Canada
24
National Bank of Canada
Quebec, Canada
$265K +$283K +147,100 New
Northern Trust
25
Northern Trust
Illinois
$246K -$310K -160,659 -54%
1
2 3 4 5

BMEA Hedge Fund Activity: Q2 2025 in Review

87 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Biomea Fusion (BMEA) for Q2 2025, worth a combined $51.7M — up 9.6% from $47.2M a quarter earlier.

Sellers outnumbered buyers: 37 funds closed out of BMEA and 29 opened new positions — a net loss of 8 holders — while 24 trimmed existing stakes and 22 added.

The largest buyer was Heights Capital Management, opening a new position worth an estimated $7.4M. The largest seller was BlackRock, cutting an estimated $2.71M.

  • 87 institutional investors held Biomea Fusion (BMEA) as of Q2 2025, down from 95 in Q1 2025.
  • Funds reported $51.7M of Biomea Fusion stock for Q2 2025, up 9.6% quarter-over-quarter.
  • 29 funds opened new Biomea Fusion positions in Q2 2025 and 37 closed out, a net change of -8 holders.
  • The largest Biomea Fusion buyer in Q2 2025 was Heights Capital Management, an estimated $7.4M added.
  • The largest Biomea Fusion seller in Q2 2025 was BlackRock, an estimated $2.71M sold.

Based on aggregated 13F filings for Q2 2025.