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Biomea Fusion
BMEA

73 hedge funds and large institutions have $50.6M invested in Biomea Fusion in 2025 Q3 according to their latest regulatory filings, with 11 funds opening new positions, 22 increasing their positions, 24 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

1% less call options, than puts

Call options by funds: $971K | Put options by funds: $982K

2% less capital invested

Capital invested by funds: $51.7M → $50.6M (-$1.11M)

8% less repeat investments, than reductions

Existing positions increased: 22 | Existing positions reduced: 24

16% less funds holding

Funds holding: 87 → 73 (-14)

34.37% less ownership

Funds ownership: 76.49% → 42.12% (-34%)

56% less first-time investments, than exits

New positions opened: 11 | Existing positions closed: 25

Holders
73
Holders Change
-14
Holders Change %
-16.09%
% of All Funds
0.96%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
11
Increased
22
Reduced
24
Closed
25
Calls
$971K
Puts
$982K
Net Calls
-$11K
Net Calls Change
-$1.64M

Top Buyers

Rank Fund Capital Flow
1
Renaissance Technologies
Renaissance Technologies
New York
+$1.09M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$683K
3
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$588K
4
Vanguard Group
Vanguard Group
Pennsylvania
+$532K
5
Marshall Wace
Marshall Wace
United Kingdom
+$477K

Top Sellers

Rank Fund Capital Flow
1
HCM
Heights Capital Management
California
-$4.4M
2
BOCH
Blue Owl Capital Holdings
New York
-$2.34M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$900K
4
Millennium Management
Millennium Management
New York
-$835K
5
WP
Woodline Partners
California
-$811K
Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$15.4M +$683K +372,940 +5%
CAM
2
Cormorant Asset Management
Massachusetts
$7.21M – – –
Vanguard Group
3
Vanguard Group
Pennsylvania
$4.38M +$532K +290,376 +15%
ACM
4
Aisling Capital Management
New York
$4.14M – – –
HCM
5
Heights Capital Management
California
$2.9M -$4.4M -2,401,703 -63%
WP
6
Woodline Partners
California
$2.63M -$811K -443,000 -25%
BlackRock
7
BlackRock
New York
$1.82M +$271K +148,004 +20%
Renaissance Technologies
8
Renaissance Technologies
New York
$1.2M +$1.09M +595,900 New
Federated Hermes
9
Federated Hermes
Pennsylvania
$1.16M -$7.91K -4,321 -0.7%
Two Sigma Investments
10
Two Sigma Investments
New York
$1.14M +$391K +213,321 +61%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$903K +$317K +173,052 +63%
Morgan Stanley
12
Morgan Stanley
New York
$895K +$104K +56,534 +15%
Susquehanna International Group
13
Susquehanna International Group
Pennsylvania
$684K +$588K +321,225 +1,845%
Marshall Wace
14
Marshall Wace
United Kingdom
$595K +$477K +260,517 +761%
Two Sigma Advisers
15
Two Sigma Advisers
New York
$539K -$55.1K -30,100 -10%
Goldman Sachs
16
Goldman Sachs
New York
$537K +$126K +68,920 +35%
XT
17
XTX Topco
Cayman Islands
$536K +$212K +115,524 +77%
SCM
18
Superstring Capital Management
New York
$505K – – –
Mariner
19
Mariner
Kansas
$483K +$438K +238,930 New
Northern Trust
20
Northern Trust
Illinois
$379K +$92.9K +50,703 +37%
Citadel Advisors
21
Citadel Advisors
Florida
$363K +$329K +179,825 New
State Street
22
State Street
Massachusetts
$283K +$72.2K +39,450 +39%
National Bank of Canada
23
National Bank of Canada
Quebec, Canada
$250K -$43K -23,500 -16%
MG
24
Marex Group
$202K +$101K +55,000 +122%
UBS Group
25
UBS Group
Switzerland
$191K -$280K -153,131 -62%
1
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BMEA Hedge Fund Activity: Q3 2025 in Review

73 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Biomea Fusion (BMEA) for Q3 2025, worth a combined $50.6M — down 2.1% from $51.7M a quarter earlier.

Sellers outnumbered buyers: 25 funds closed out of BMEA and 11 opened new positions — a net loss of 14 holders — while 24 trimmed existing stakes and 22 added.

The largest buyer was Renaissance Technologies, opening a new position worth an estimated $1.09M. The largest seller was Heights Capital Management, cutting an estimated $4.4M.

  • 73 institutional investors held Biomea Fusion (BMEA) as of Q3 2025, down from 87 in Q2 2025.
  • Funds reported $50.6M of Biomea Fusion stock for Q3 2025, down 2.1% quarter-over-quarter.
  • 11 funds opened new Biomea Fusion positions in Q3 2025 and 25 closed out, a net change of -14 holders.
  • The largest Biomea Fusion buyer in Q3 2025 was Renaissance Technologies, an estimated $1.09M added.
  • The largest Biomea Fusion seller in Q3 2025 was Heights Capital Management, an estimated $4.4M sold.

Based on aggregated 13F filings for Q3 2025.