Two Sigma Advisers
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Two Sigma Advisers’s Olema Pharmaceuticals OLMA Stock Holding History

Two Sigma Advisers’s Portfolio OLMA Stock Details OLMA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-21,100
Closed -$207K – 2541
2025
Q3 		$207K Sell
21,100
-123,300
-85% -$740K ﹤0.01% 2124
2025
Q2 		$615K Buy
144,400
+6,400
+5% +$28.5K ﹤0.01% 1655
2025
Q1 		$519K Buy
138,000
+49,000
+55% +$246K ﹤0.01% 1763
2024
Q4 		$519K Sell
89,000
-12,200
-12% -$122K ﹤0.01% 1762
2024
Q3 		$1.21M Sell
101,200
-28,300
-22% -$362K ﹤0.01% 1321
2024
Q2 		$1.4M Sell
129,500
-19,000
-13% -$206K ﹤0.01% 1386
2024
Q1 		$1.68M Sell
148,500
-32,300
-18% -$417K ﹤0.01% 1312
2023
Q4 		$2.54M Sell
180,800
-59,000
-25% -$793K 0.01% 1154
2023
Q3 		$2.96M Sell
239,800
-1,100
-0.5% -$11.2K 0.01% 992
2023
Q2 		$2.18M Buy
240,900
+35,000
+17% +$211K 0.01% 1153
2023
Q1 		$714K Sell
205,900
-20,500
-9% -$83.6K ﹤0.01% 1794
2022
Q4 		$555K Sell
226,400
-158,100
-41% -$461K ﹤0.01% 1841
2022
Q3 		$1.06M Sell
384,500
-129,300
-25% -$548K ﹤0.01% 1493
2022
Q2 		$2.09M Sell
513,800
-101,600
-17% -$322K 0.01% 1190
2022
Q1 		$2.62M Buy
615,400
+47,400
+8% +$261K 0.01% 1098
2021
Q4 		$5.32M Buy
568,000
+558,700
+6,008% +$11.6M 0.01% 737
2021
Q3 		$256K Buy
+9,300
New +$251K ﹤0.01% 2176

Other funds holding OLMA

BCLSI
Bain Capital Life Sciences Investors Boston, Massachusetts $1.11B AUM 171.34% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
LGM
Logos Global Management San Francisco, California $2B AUM 444.09% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return

Two Sigma Advisers's OLMA Position: Q4 2025 in Review

Two Sigma Advisers sold out of Olema Pharmaceuticals (OLMA) in Q4 2025, closing a stake of 21,100 shares — an estimated $207K sold.

Two Sigma Advisers first reported a position in OLMA in Q3 2021 and held it in 17 quarters. The position peaked at $5.32M in Q4 2021. 200 funds tracked by Wall St. Rank hold OLMA as of Q4 2025.

  • Two Sigma Advisers reported no remaining Olema Pharmaceuticals position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Advisers sold 21,100 Olema Pharmaceuticals shares in Q4 2025, an estimated $207K.
  • Two Sigma Advisers first reported a position in Olema Pharmaceuticals in Q3 2021 and held it in 17 quarters.
  • Two Sigma Advisers's Olema Pharmaceuticals position peaked at $5.32M in Q4 2021.
  • 200 funds tracked by Wall St. Rank held Olema Pharmaceuticals as of Q4 2025.

Based on Two Sigma Advisers's 13F filing for Q4 2025, filed 17 Feb 2026.