We are live on ! Find out more
OLMA icon

Olema Pharmaceuticals
OLMA

200 hedge funds and large institutions have $2.27B invested in Olema Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 87 funds opening new positions, 55 increasing their positions, 39 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

625% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 12

450% more funds holding in top 10

Funds holding in top 10: 2 → 11 (+9)

239% more capital invested

Capital invested by funds: $668M → $2.27B (+$1.6B)

76% more call options, than puts

Call options by funds: $30.8M | Put options by funds: $17.5M

59% more funds holding

Funds holding: 126 → 200 (+74)

41% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 39

32.66% more ownership

Funds ownership: 99.49% → 132.15% (+33%)

Holders
200
Holders Change
+74
Holders Change %
+58.73%
% of All Funds
2.43%
Holding in Top 10
11
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+450%
% of All Funds
0.13%
New
87
Increased
55
Reduced
39
Closed
12
Calls
$30.8M
Puts
$17.5M
Net Calls
+$13.3M
Net Calls Change
+$7.65M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$88.9M
2
SL
Siren LLC
Connecticut
+$58.7M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$55.6M
4
CAM
Cormorant Asset Management
Massachusetts
+$48.9M
5
RCM
RA Capital Management
Massachusetts
+$46.3M

Top Sellers

1
DTC
Deep Track Capital
Connecticut
-$34M
2
Pictet Asset Management
Pictet Asset Management
Switzerland
-$20.2M
3
Ameriprise
Ameriprise
Minnesota
-$16.8M
4
UBS Group
UBS Group
Switzerland
-$16M
5
Morgan Stanley
Morgan Stanley
New York
-$15.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$213M +$29.6M +1,664,687 +24%
PBA
2
Paradigm Biocapital Advisors
New York
$189M +$13.3M +750,000 +11%
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$168M +$55.6M +3,124,345 +87%
BlackRock
4
BlackRock
New York
$139M +$14.9M +836,866 +18%
BI
5
BVF Inc
California
$132M – – –
Fidelity Investments
6
Fidelity Investments
Massachusetts
$126M +$88.9M +4,993,670 +16,973%
Vanguard Group
7
Vanguard Group
Pennsylvania
$89M +$6.48M +364,035 +11%
SL
8
Siren LLC
Connecticut
$82.5M +$58.7M +3,300,700 New
LGM
9
Logos Global Management
California
$80.2M – – –
CAM
10
Cormorant Asset Management
Massachusetts
$68.8M +$48.9M +2,750,000 New
RCM
11
RA Capital Management
Massachusetts
$65M +$46.3M +2,600,000 New
Franklin Resources
12
Franklin Resources
California
$61.9M -$9.53M -535,304 -18%
LMC
13
Lightspeed Management Company
California
$48.3M – – –
State Street
14
State Street
Massachusetts
$47.1M +$14.1M +790,825 +72%
VPC
15
Vestal Point Capital
New York
$41.3M +$29.4M +1,650,000 New
WP
16
Woodline Partners
California
$37M -$13.1M -735,963 -33%
PCH
17
Polar Capital Holdings
United Kingdom
$34.5M +$24.6M +1,380,450 New
Geode Capital Management
18
Geode Capital Management
Massachusetts
$31.4M -$330K -18,564 -1%
DCM
19
Defilade Capital Management
California
$30.9M +$22M +1,234,634 New
Citadel Advisors
20
Citadel Advisors
Florida
$30M -$651K -36,608 -3%
T. Rowe Price Associates
21
T. Rowe Price Associates
Maryland
$27.4M +$18.9M +1,064,254 +3,349%
SC
22
Samlyn Capital
New York
$26.7M +$19M +1,069,543 New
Jennison Associates
23
Jennison Associates
New York
$24.1M +$17.2M +963,997 New
Dimensional Fund Advisors
24
Dimensional Fund Advisors
Texas
$24M -$1.88M -105,905 -10%
KCM
25
Kingdon Capital Management
New York
$23.8M +$1.77M +99,600 +12%
1
2 3 4 5

OLMA Hedge Fund Activity: Q4 2025 in Review

200 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Olema Pharmaceuticals (OLMA) for Q4 2025, worth a combined $2.27B — up 239% from $668M a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new OLMA positions and 12 closed out — a net gain of 75 holders — while 55 added to existing stakes and 39 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $88.9M. The largest seller was Deep Track Capital, exiting entirely with an estimated $34M sold.

  • 200 institutional investors held Olema Pharmaceuticals (OLMA) as of Q4 2025, up from 126 in Q3 2025.
  • Funds reported $2.27B of Olema Pharmaceuticals stock for Q4 2025, up 239% quarter-over-quarter.
  • 87 funds opened new Olema Pharmaceuticals positions in Q4 2025 and 12 closed out, a net change of +75 holders.
  • The largest Olema Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $88.9M added.
  • The largest Olema Pharmaceuticals seller in Q4 2025 was Deep Track Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q4 2025.