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Olema Pharmaceuticals
OLMA

195 hedge funds and large institutions have $1.51B invested in Olema Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 46 funds opening new positions, 73 increasing their positions, 51 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

272% more call options, than puts

Call options by funds: $41.3M | Put options by funds: $11.1M

43% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 51

8% less first-time investments, than exits

New positions opened: 46 | Existing positions closed: 50

3% less funds holding

Funds holding: 200 → 195 (-5)

15.73% less ownership

Funds ownership: 132.15% → 116.42% (-16%)

33% less capital invested

Capital invested by funds: $2.27B → $1.51B (-$755M)

73% less funds holding in top 10

Funds holding in top 10: 11 → 3 (-8)

Holders
195
Holders Change
-5
Holders Change %
-2.5%
% of All Funds
2.4%
Holding in Top 10
3
Holding in Top 10 Change
-8
Holding in Top 10 Change %
-72.73%
% of All Funds
0.04%
New
46
Increased
73
Reduced
51
Closed
50
Calls
$41.3M
Puts
$11.1M
Net Calls
+$30.2M
Net Calls Change
+$16.9M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$119M
2
State Street
State Street
Massachusetts
+$45.7M
3
SL
Siren LLC
Connecticut
+$32.4M
4
CAM
Cormorant Asset Management
Massachusetts
+$25.6M
5
DFO
Duquesne Family Office
New York
+$22M

Top Sellers

1
Franklin Resources
Franklin Resources
California
-$28M
2
VPC
Vestal Point Capital
New York
-$27.2M
3
SC
Samlyn Capital
New York
-$26.7M
4
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
-$23M
5
EAM
Eventide Asset Management
Massachusetts
-$14.2M
Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$155M +$119M +5,363,753 +107%
PBA
2
Paradigm Biocapital Advisors
New York
$120M +$10.6M +476,404 +6%
BCLSI
3
Bain Capital Life Sciences Investors
Massachusetts
$111M -$23M -1,035,403 -12%
Janus Henderson Group
4
Janus Henderson Group
United Kingdom
$106M +$8.87M +398,294 +6%
BlackRock
5
BlackRock
New York
$84.3M +$1.98M +88,875 +2%
BI
6
BVF Inc
California
$79M – – –
SL
7
Siren LLC
Connecticut
$70.9M +$32.4M +1,456,249 +44%
State Street
8
State Street
Massachusetts
$58.7M +$45.7M +2,053,432 +109%
CAM
9
Cormorant Asset Management
Massachusetts
$58.1M +$25.6M +1,150,000 +42%
LGM
10
Logos Global Management
California
$47.8M – – –
VCM
11
Vanguard Capital Management
Pennsylvania
$46M +$68.6M +3,083,517 New
RCM
12
RA Capital Management
Massachusetts
$38.8M – – –
Jennison Associates
13
Jennison Associates
New York
$27.2M +$19.1M +858,126 +89%
PCH
14
Polar Capital Holdings
United Kingdom
$23.9M +$4.95M +222,520 +16%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$23M +$6.39M +286,976 +23%
DCM
16
Defilade Capital Management
California
$22.4M +$6.01M +269,902 +22%
WP
17
Woodline Partners
California
$22.1M +$2.23K +100 +0%
LMC
18
Lightspeed Management Company
California
$20.2M -$12.8M -575,595 -30%
Franklin Resources
19
Franklin Resources
California
$18.2M -$28M -1,257,708 -51%
Morgan Stanley
20
Morgan Stanley
New York
$18.1M +$12.2M +549,887 +83%
T. Rowe Price Associates
21
T. Rowe Price Associates
Maryland
$17.6M +$1.93M +86,801 +8%
Two Sigma Investments
22
Two Sigma Investments
New York
$17.4M +$17.3M +775,763 +197%
Dimensional Fund Advisors
23
Dimensional Fund Advisors
Texas
$16.1M +$2.76M +123,790 +13%
Goldman Sachs
24
Goldman Sachs
New York
$15.6M +$5.07M +227,700 +28%
DFO
25
Duquesne Family Office
New York
$14.7M +$22M +986,827 New
1
2 3 4 5

OLMA Hedge Fund Activity: Q1 2026 in Review

195 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Olema Pharmaceuticals (OLMA) for Q1 2026, worth a combined $1.51B — down 33% from $2.27B a quarter earlier.

Sellers outnumbered buyers: 50 funds closed out of OLMA and 46 opened new positions — a net loss of 4 holders — while 51 trimmed existing stakes and 73 added.

The largest buyer was Fidelity Investments, adding an estimated $119M. The largest seller was Franklin Resources, cutting an estimated $28M.

  • 195 institutional investors held Olema Pharmaceuticals (OLMA) as of Q1 2026, down from 200 in Q4 2025.
  • Funds reported $1.51B of Olema Pharmaceuticals stock for Q1 2026, down 33% quarter-over-quarter.
  • 46 funds opened new Olema Pharmaceuticals positions in Q1 2026 and 50 closed out, a net change of -4 holders.
  • The largest Olema Pharmaceuticals buyer in Q1 2026 was Fidelity Investments, an estimated $119M added.
  • The largest Olema Pharmaceuticals seller in Q1 2026 was Franklin Resources, an estimated $28M sold.

Based on aggregated 13F filings for Q1 2026.