Two Sigma Advisers
APLS

Two Sigma Advisers’s Apellis Pharmaceuticals APLS Stock Holding History

Two Sigma Advisers’s Portfolio APLS Stock Details APLS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-110,900
Closed -$2.79M – 143
2025
Q4 		$2.79M Buy
+110,900
New +$2.6M 0.01% 1056
2025
Q3 		– Sell
-256,800
Closed -$4.45M – 2343
2025
Q2 		$4.45M Buy
256,800
+65,000
+34% +$1.2M 0.01% 781
2025
Q1 		$4.19M Buy
+191,800
New +$5.3M 0.01% 853
2022
Q1 		– Sell
-30,600
Closed -$1.45M – 2724
2021
Q4 		$1.45M Sell
30,600
-461,000
-94% -$18.1M ﹤0.01% 1356
2021
Q3 		$16.2M Sell
491,600
-132,300
-21% -$7.43M 0.04% 365
2021
Q2 		$39.4M Sell
623,900
-63,500
-9% -$3.28M 0.1% 203
2021
Q1 		$29.5M Sell
687,400
-21,200
-3% -$1M 0.08% 262
2020
Q4 		$40.5M Sell
708,600
-103,600
-13% -$4.38M 0.11% 202
2020
Q3 		$24.5M Sell
812,200
-109,000
-12% -$3.26M 0.07% 268
2020
Q2 		$30.1M Buy
921,200
+44,000
+5% +$1.41M 0.09% 238
2020
Q1 		$23.5M Buy
877,200
+617,200
+237% +$21.9M 0.09% 260
2019
Q4 		$7.96M Buy
260,000
+189,300
+268% +$5.24M 0.02% 668
2019
Q3 		$1.7M Buy
+70,700
New +$1.95M ﹤0.01% 1181

Other funds holding APLS

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
PCM
Pentwater Capital Management Naples, Florida $19.3B AUM 58.13% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
DTC
Deep Track Capital Greenwich, Connecticut $6.87B AUM 205.24% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $90.7B AUM 77.13% 1-Year Est. Return

Two Sigma Advisers's APLS Position: Q1 2026 in Review

Two Sigma Advisers sold out of Apellis Pharmaceuticals (APLS) in Q1 2026, closing a stake of 110,900 shares — an estimated $2.79M sold.

Two Sigma Advisers first reported a position in APLS in Q3 2019 and held it in 13 quarters. The position peaked at $40.5M in Q4 2020. 323 funds tracked by Wall St. Rank hold APLS as of Q1 2026.

  • Two Sigma Advisers reported no remaining Apellis Pharmaceuticals position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 110,900 Apellis Pharmaceuticals shares in Q1 2026, an estimated $2.79M.
  • Two Sigma Advisers first reported a position in Apellis Pharmaceuticals in Q3 2019 and held it in 13 quarters.
  • Two Sigma Advisers's Apellis Pharmaceuticals position peaked at $40.5M in Q4 2020.
  • 323 funds tracked by Wall St. Rank held Apellis Pharmaceuticals as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.