State Street
SION

State Street’s Sionna Therapeutics SION Stock Holding History

State Street’s Portfolio SION Stock Details SION Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$30.3M Buy
756,227
+62,832
+9% +$2.4M ﹤0.01% 2005
2025
Q4 		$28.5M Buy
693,395
+453,196
+189% +$17.2M ﹤0.01% 2056
2025
Q3 		$7.06M Buy
240,199
+115,681
+93% +$2.52M ﹤0.01% 2828
2025
Q2 		$2.16M Buy
124,518
+110,118
+765% +$1.44M ﹤0.01% 3290
2025
Q1 		$151K Buy
+14,400
New +$235K ﹤0.01% 3889

Other funds holding SION

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGA
TPG GP A Fort Worth, Texas $3.68B AUM 14.99% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
Viking Global Investors
Viking Global Investors Stamford, Connecticut $35.7B AUM 21.3% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $790M AUM 223.66% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
Jennison Associates
Jennison Associates New York $145B AUM 34.61% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

State Street's SION Position: Q1 2026 in Review

State Street increased its Sionna Therapeutics (SION) stake by 9.1% in Q1 2026, buying an estimated $2.4M and bringing the position to 756,227 shares worth $30.3M. The position accounts for ﹤0.01% of the portfolio, ranked #2005.

State Street first reported a position in SION in Q1 2025 and has held it in 5 quarters since. 122 funds tracked by Wall St. Rank hold SION as of Q1 2026.

  • State Street held 756,227 shares of Sionna Therapeutics worth $30.3M as of Q1 2026.
  • State Street bought 62,832 Sionna Therapeutics shares in Q1 2026, an estimated $2.4M.
  • Sionna Therapeutics made up ﹤0.01% of State Street's portfolio in Q1 2026, its #2005 holding.
  • State Street first reported a position in Sionna Therapeutics in Q1 2025 and has held it in 5 quarters since.
  • 122 funds tracked by Wall St. Rank held Sionna Therapeutics as of Q1 2026.

Based on State Street's 13F filing for Q1 2026, filed 15 May 2026.