State Street
SION

State Street’s Sionna Therapeutics SION Stock Holding History

State Street’s Portfolio SION Stock Details SION Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$44.9M Buy
1,021,534
+265,307
+35% +$10.6M ﹤0.01% 1908
2026
Q1 		$30.3M Buy
756,227
+62,832
+9% +$2.4M ﹤0.01% 2005
2025
Q4 		$28.5M Buy
693,395
+453,196
+189% +$17.2M ﹤0.01% 2056
2025
Q3 		$7.06M Buy
240,199
+115,681
+93% +$2.52M ﹤0.01% 2828
2025
Q2 		$2.16M Buy
124,518
+110,118
+765% +$1.44M ﹤0.01% 3290
2025
Q1 		$151K Buy
+14,400
New +$235K ﹤0.01% 3889

Other funds holding SION

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGA
TPG GP A Fort Worth, Texas $5B AUM 58.56% 1-Year Est. Return
Viking Global Investors
Viking Global Investors Stamford, Connecticut $35.1B AUM 21.36% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $881M AUM 160.77% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return
Jennison Associates
Jennison Associates New York $167B AUM 44.17% 1-Year Est. Return

State Street's SION Position: Q2 2026 in Review

State Street increased its Sionna Therapeutics (SION) stake by 35% in Q2 2026, buying an estimated $10.6M and bringing the position to 1,021,534 shares worth $44.9M. The position accounts for ﹤0.01% of the portfolio, ranked #1908.

State Street first reported a position in SION in Q1 2025 and has held it in 6 quarters since. 146 funds tracked by Wall St. Rank hold SION as of Q2 2026.

  • State Street held 1,021,534 shares of Sionna Therapeutics worth $44.9M as of Q2 2026.
  • State Street bought 265,307 Sionna Therapeutics shares in Q2 2026, an estimated $10.6M.
  • Sionna Therapeutics made up ﹤0.01% of State Street's portfolio in Q2 2026, its #1908 holding.
  • State Street first reported a position in Sionna Therapeutics in Q1 2025 and has held it in 6 quarters since.
  • 146 funds tracked by Wall St. Rank held Sionna Therapeutics as of Q2 2026.

Based on State Street's 13F filing for Q2 2026, filed 7 Aug 2026.