SION

Sionna Therapeutics, Inc. Common Stock
SION

Overview Fund Activity

65 hedge funds and large institutions have $754M invested in Sionna Therapeutics, Inc. Common Stock in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 18 increasing their positions, 10 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
65
Holders Change
+18
Holders Change %
+38.3%
% of All Funds
0.87%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.05%
New
26
Increased
18
Reduced
10
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
B
Braidwell
Connecticut
$18.8M
2
BlackRock
BlackRock
New York
$11.1M
3
Viking Global Investors
Viking Global Investors
Connecticut
$55.4M
4
DM
Deerfield Management
New York
$16.8M
5
Aberdeen Group
Aberdeen Group
United Kingdom
$16.5M

Top Sellers

1
DCM
Driehaus Capital Management
Illinois
$1.45M
2
Citadel Advisors
Citadel Advisors
Florida
$2.25M
3
Millennium Management
Millennium Management
New York
$243K
4
ZP
Zimmer Partners
New York
$0
5
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$14.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
RCM
1
RA Capital Management
Massachusetts
$181M – – –
TGA
2
TPG GP A
Texas
$117M +$1.04M +60,000 +0.9%
O
3
OrbiMed
New York
$64.3M – – –
AVLSA
4
Atlas Venture Life Science Advisors
Massachusetts
$64.1M – – –
Viking Global Investors
5
Viking Global Investors
Connecticut
$55.4M +$4.21M +242,427 +8%
ES
6
Enavate Sciences
California
$43M – – –
JPMorgan Chase & Co
7
JPMorgan Chase & Co
New York
$38.5M +$895K +51,589 +2%
PA
8
Perceptive Advisors
New York
$21.1M -$608K -35,056 -3%
B
9
Braidwell
Connecticut
$18.8M +$18.8M +1,081,855 New
DM
10
Deerfield Management
New York
$16.8M +$3.88M +223,590 +30%
Aberdeen Group
11
Aberdeen Group
United Kingdom
$16.5M +$3.55M +204,583 +27%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$14.9M -$2.34M -134,974 -14%
Jennison Associates
13
Jennison Associates
New York
$13.1M -$1.86M -107,127 -12%
BlackRock
14
BlackRock
New York
$11.1M +$7.61M +438,708 +221%
Vanguard Group
15
Vanguard Group
Pennsylvania
$10.9M +$1.46M +84,184 +15%
Franklin Resources
16
Franklin Resources
California
$8.68M – – –
BBA
17
Baker Bros. Advisors
New York
$6.94M – – –
SCM
18
Soleus Capital Management
Connecticut
$6.52M +$2.36M +136,000 +57%
SL
19
Siren LLC
Connecticut
$5.64M – – –
Geode Capital Management
20
Geode Capital Management
Massachusetts
$5.02M +$2.67M +153,712 +113%
Ameriprise
21
Ameriprise
Minnesota
$4.11M +$478K +27,547 +13%
Alyeska Investment Group
22
Alyeska Investment Group
Illinois
$3.23M – – –
SCM
23
Silverarc Capital Management
Massachusetts
$3.23M +$1.25M +71,877 +63%
Prudential Financial
24
Prudential Financial
New Jersey
$2.35M +$1.25M +72,185 +115%
Citadel Advisors
25
Citadel Advisors
Florida
$2.25M -$3.41M -196,588 -60%
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