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Sio Capital Management’s Annexon ANNX Stock Holding History

Sio Capital Management’s Portfolio ANNX Stock Details ANNX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-4,095,764
Closed -$9.83M – 53
2025
Q2 		$9.83M Buy
4,095,764
+697,978
+21% +$1.4M 3.75% 9
2025
Q1 		$6.56M Buy
3,397,786
+1,030,779
+44% +$3.43M 1.95% 14
2024
Q4 		$12.1M Buy
2,367,007
+933,852
+65% +$5.75M 3.42% 9
2024
Q3 		$8.48M Buy
+1,433,155
New +$8.5M 3.36% 12

Other funds holding ANNX

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
RG
Redmile Group San Francisco, California $1.51B AUM 164.17% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BCLSI
Bain Capital Life Sciences Investors Boston, Massachusetts $1.11B AUM 171.34% 1-Year Est. Return
BG
Bellevue Group Kuesnacht, Switzerland $4.2B AUM 54.85% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return

Sio Capital Management's ANNX Position: Q3 2025 in Review

Sio Capital Management sold out of Annexon (ANNX) in Q3 2025, closing a stake of 4,095,764 shares — an estimated $9.83M sold.

Sio Capital Management first reported a position in ANNX in Q3 2024 and held it in 4 quarters. The position peaked at $12.1M in Q4 2024. 144 funds tracked by Wall St. Rank hold ANNX as of Q3 2025.

  • Sio Capital Management reported no remaining Annexon position as of Q3 2025 after selling out during the quarter.
  • Sio Capital Management sold 4,095,764 Annexon shares in Q3 2025, an estimated $9.83M.
  • Sio Capital Management first reported a position in Annexon in Q3 2024 and held it in 4 quarters.
  • Sio Capital Management's Annexon position peaked at $12.1M in Q4 2024.
  • 144 funds tracked by Wall St. Rank held Annexon as of Q3 2025.

Based on Sio Capital Management's 13F filing for Q3 2025, filed 13 Nov 2025.