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SAM

Simplify Asset Management Portfolio holdings

AUM $7.19B
1-Year Est. Return 6.88%
This Fund
S&P 500
This Quarter Est. Return
+0.82%
1 Year Est. Return
+6.88%
3 Year Est. Return
+44.98%
5 Year Est. Return
+50.08%
10 Year Est. Return
–
AUM
$6.13B
AUM Growth
+$696M
Cap. Flow
+$703M
Cap. Flow %
11.47%
Top 10 Hldgs %
92.45%
Holding
166
New
37
Increased
75
Reduced
18
Closed
24

Top Buys

Rank Stock Value
1
SBIL
Simplify Government Money Market ETF
SBIL
+$1.05B
2
UNH icon
UnitedHealth
UNH
+$23.9M
3
LLY icon
Eli Lilly
LLY
+$17.5M
4
AMGN icon
Amgen
AMGN
+$16.6M
5
ALGN icon
Align Technology
ALGN
+$15.4M

Top Sells

Rank Stock Value
1
AGGH icon
Simplify Aggregate Bond ETF
AGGH
+$38.7M
2
QIS icon
Simplify Multi-QIS Alternative ETF
QIS
+$15M
3
FOXY
Simplify Currency Strategy ETF
FOXY
+$9.3M
4
XV
Simplify Target 15 Distribution ETF
XV
+$9.29M
5
SBAR
Simplify Barrier Income ETF
SBAR
+$7.17M

Sector Composition

Rank Sector Weight
1 Healthcare 5.76%
2 Energy 0.41%
3 Industrials 0.31%
4 Technology 0.2%
5 Real Estate 0.16%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VRTX icon
26
Vertex Pharmaceuticals
VRTX
$126B
$7.93M 0.13%
17,492
+16,267
+1,328% +$7.01M
TXG icon
27
10x Genomics
TXG
$6.61B
$7.93M 0.13%
+485,977
New +$7.34M
EYPT icon
28
EyePoint Inc
EYPT
$1.2B
$6.86M 0.11%
375,264
+284,824
+315% +$4.04M
AZN icon
29
AstraZeneca
AZN
$250B
$6.53M 0.11%
35,490
+17,018
+92% +$2.98M
INSM icon
30
Insmed
INSM
$28.6B
$6.42M 0.1%
36,890
+17,226
+88% +$3.14M
ACHV icon
31
Achieve Life Sciences
ACHV
$683M
$5.89M 0.1%
1,184,512
– –
CVS icon
32
CVS Health
CVS
$122B
$5.88M 0.1%
74,124
-10,802
-13% -$852K
TSLA icon
33
Tesla
TSLA
$1.3T
$5.78M 0.09%
12,843
-11,517
-47% -$5.11M
ABBV icon
34
AbbVie
ABBV
$435B
$5.43M 0.09%
23,777
-13,106
-36% -$2.99M
PHAT icon
35
Phathom Pharmaceuticals
PHAT
$692M
$5.34M 0.09%
321,935
– –
ESTA icon
36
Establishment Labs
ESTA
$2.28B
$5.31M 0.09%
72,894
+34,946
+92% +$2.11M
ALHC icon
37
Alignment Healthcare
ALHC
$2.98B
$5.19M 0.08%
262,880
+125,946
+92% +$2.26M
PEN icon
38
Penumbra
PEN
$12.8B
$4.92M 0.08%
15,827
+7,485
+90% +$2.07M
QQQ icon
39
PUT
Invesco QQQ Trust
QQQ
$484B
$4.9M 0.08%
+8,000
New +$4.91M
HODL icon
40
VanEck Bitcoin Trust
HODL
$1.08B
$4.77M 0.08%
192,930
-42,062
-18% -$1.19M
GILD icon
41
Gilead Sciences
GILD
$165B
$4.6M 0.08%
37,479
-22,707
-38% -$2.76M
JNJ icon
42
Johnson & Johnson
JNJ
$625B
$4.54M 0.07%
21,960
+10,558
+93% +$2.09M
GEHC icon
43
GE HealthCare
GEHC
$32.4B
$4.43M 0.07%
54,028
+25,844
+92% +$2.01M
MLYS icon
44
Mineralys Therapeutics
MLYS
$2.41B
$4.14M 0.07%
114,182
-104,544
-48% -$4.19M
IQV icon
45
IQVIA
IQV
$39.3B
$3.93M 0.06%
17,418
+8,374
+93% +$1.82M
VRDN icon
46
Viridian Therapeutics
VRDN
$2.67B
$3.22M 0.05%
103,531
+53,531
+107% +$1.47M
XXV
47
Simplify Ancorato Target 25 Distribution ETF
XXV
$51.1M
$3.18M 0.05%
+125,000
New +$3.2M
MIST icon
48
Milestone Pharmaceuticals
MIST
$152M
$3.04M 0.05%
1,506,405
-1,326,569
-47% -$2.86M
GH icon
49
Guardant Health
GH
$22.6B
$3.02M 0.05%
29,581
-1,519
-5% -$136K
OSCR icon
50
Oscar Health
OSCR
$8.61B
$2.95M 0.05%
+205,131
New +$3.55M
1
2
3 4 5

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UB
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TSC
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FPA
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SC
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GLF
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Simplify Asset Management's Q4 2025 Portfolio in Review

As of Q4 2025, Simplify Asset Management held 166 positions worth $6.13B, up 13% from $5.43B the previous quarter. Its ten largest holdings account for 92% of the portfolio.

Simplify Asset Management deployed $703M of net new capital in Q4 2025, opening 37 new positions and adding to 75 existing holdings. Its largest new stake was Amgen: 52,350 shares worth $17.1M.

By sector, the portfolio is most concentrated in Healthcare at 5.8% of assets, up from 3.3% a quarter earlier, followed by Energy and Industrials.

On the sell side, the largest reduction was Simplify Aggregate Bond ETF, an estimated $38.7M trimmed.

  • Simplify Asset Management's largest Q4 2025 buy was Amgen: 52,350 shares worth $17.1M.
  • Simplify Asset Management added most to Simplify Government Money Market ETF in Q4 2025, an estimated $1.05B increase.
  • Simplify Asset Management's biggest Q4 2025 reduction was Simplify Aggregate Bond ETF, cutting an estimated $38.7M.
  • Simplify Asset Management fully exited Simplify Currency Strategy ETF in Q4 2025, selling an estimated $9.3M.
  • Simplify Asset Management's ten largest holdings make up 92% of its $6.13B portfolio in Q4 2025.
  • Simplify Asset Management opened 37 new positions and closed 24 in Q4 2025.
  • Simplify Asset Management's portfolio value rose 13% quarter-over-quarter to $6.13B.

Based on Simplify Asset Management's 13F filing for Q4 2025, filed 9 Feb 2026.