Simplex Trading’s Pyxis Oncology PYXS Stock Holding History

Simplex Trading’s Portfolio PYXS Stock Details PYXS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$3.61K	Sell	1,200 -26,500	-96%	-$50.7K	﹤0.01%	8357
2026 Q1	$40.4K	Sell	27,700 -55,700	-67%	-$84K	﹤0.01%	6094
2025 Q4	$95.9K	Buy	83,400 +64,700	+346%	+$228K	﹤0.01%	5039
2025 Q3	$41K	Buy	+18,700	New	+$26.9K	﹤0.01%	6657
2025 Q2	–	Sell	-7,200	Closed	-$7K	–	9534
2025 Q1	$7K	Sell	7,200 -36,300	-83%	-$48.4K	﹤0.01%	7362
2024 Q4	$67K	Buy	43,500 +30,600	+237%	+$88.3K	﹤0.01%	5568
2024 Q3	$47K	Sell	12,900 -200	-2%	-$700	﹤0.01%	5937
2024 Q2	$43K	Sell	13,100 -5,700	-30%	-$24K	﹤0.01%	6231
2024 Q1	$80K	Buy	18,800 +18,200	+3,033%	+$76.5K	﹤0.01%	5817
2023 Q4	$1K	Buy	+600	New	+$1.03K	﹤0.01%	8565
2023 Q3	–	Sell	-1,400	Closed	-$3K	–	9600
2023 Q2	$3K	Buy	+1,400	New	+$4.44K	﹤0.01%	8266

Other funds holding PYXS

GGI

GordonMD Global Investments Beverely Hills, California $207M AUM

Pfizer New York $170M AUM 191.09% 1-Year Est. Return

LCM

Laurion Capital Management New York $3.9B AUM 75.03% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

HealthInvest Partners Stockholm, Sweden $372M AUM 59.89% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

PAI

Palo Alto Investors Palo Alto, California $724M AUM 96.91% 1-Year Est. Return

Marshall Wace London, United Kingdom $127B AUM 46.06% 1-Year Est. Return

Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

Simplex Trading's PYXS Position: Q2 2026 in Review

Simplex Trading increased its Pyxis Oncology (PYXS) stake by 14,881% in Q2 2026, buying an estimated $72K and bringing the position to 37,902 shares worth $114K. The position accounts for ﹤0.01% of the portfolio, ranked #5384.

Simplex Trading first reported a position in PYXS in Q2 2023 and has held it in 11 quarters since. The position peaked at $134K in Q2 2024. 76 funds tracked by Wall St. Rank hold PYXS as of Q2 2026.

Simplex Trading held 37,902 shares of Pyxis Oncology worth $114K as of Q2 2026.
Simplex Trading bought 37,649 Pyxis Oncology shares in Q2 2026, an estimated $72K.
Pyxis Oncology made up ﹤0.01% of Simplex Trading's portfolio in Q2 2026, its #5384 holding.
Simplex Trading first reported a position in Pyxis Oncology in Q2 2023 and has held it in 11 quarters since.
Simplex Trading's Pyxis Oncology position peaked at $134K in Q2 2024.
76 funds tracked by Wall St. Rank held Pyxis Oncology as of Q2 2026.

Based on Simplex Trading's 13F filing for Q2 2026, filed 12 Aug 2026.