Simplex Trading
PYXS icon

Simplex Trading’s Pyxis Oncology PYXS Stock Holding History

Simplex Trading’s Portfolio PYXS Stock Details PYXS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$40.4K Sell
27,700
-55,700
-67% -$84K ﹤0.01% 6094
2025
Q4 		$95.9K Buy
83,400
+64,700
+346% +$228K ﹤0.01% 5039
2025
Q3 		$41K Buy
+18,700
New +$26.9K ﹤0.01% 6657
2025
Q2 		– Sell
-7,200
Closed -$7K – 9534
2025
Q1 		$7K Sell
7,200
-36,300
-83% -$48.4K ﹤0.01% 7362
2024
Q4 		$67K Buy
43,500
+30,600
+237% +$88.3K ﹤0.01% 5568
2024
Q3 		$47K Sell
12,900
-200
-2% -$700 ﹤0.01% 5937
2024
Q2 		$43K Sell
13,100
-5,700
-30% -$24K ﹤0.01% 6231
2024
Q1 		$80K Buy
18,800
+18,200
+3,033% +$76.5K ﹤0.01% 5817
2023
Q4 		$1K Buy
+600
New +$1.03K ﹤0.01% 8565
2023
Q3 		– Sell
-1,400
Closed -$3K – 9600
2023
Q2 		$3K Buy
+1,400
New +$4.44K ﹤0.01% 8266

Other funds holding PYXS

P
Pfizer New York $239M AUM 232.47% 1-Year Est. Return
LCM
Laurion Capital Management New York $2.29B AUM 75.73% 1-Year Est. Return
GGI
GordonMD Global Investments Beverely Hills, California $144M AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
HP
HealthInvest Partners Stockholm, Sweden $310M AUM 37.86% 1-Year Est. Return
PAI
Palo Alto Investors Palo Alto, California $654M AUM 77.8% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Simplex Trading's PYXS Position: Q1 2026 in Review

Simplex Trading reduced its Pyxis Oncology (PYXS) stake by 97% in Q1 2026, selling an estimated $14.4K and leaving 253 shares worth $369. The position accounts for ﹤0.01% of the portfolio, ranked #8767.

Simplex Trading first reported a position in PYXS in Q2 2023 and has held it in 10 quarters since. The position peaked at $134K in Q2 2024. 78 funds tracked by Wall St. Rank hold PYXS as of Q1 2026.

  • Simplex Trading held 253 shares of Pyxis Oncology worth $369 as of Q1 2026.
  • Simplex Trading sold 9,537 Pyxis Oncology shares in Q1 2026, an estimated $14.4K.
  • Pyxis Oncology made up ﹤0.01% of Simplex Trading's portfolio in Q1 2026, its #8767 holding.
  • Simplex Trading first reported a position in Pyxis Oncology in Q2 2023 and has held it in 10 quarters since.
  • Simplex Trading's Pyxis Oncology position peaked at $134K in Q2 2024.
  • 78 funds tracked by Wall St. Rank held Pyxis Oncology as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.