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Silverarc Capital Management’s Spyre Therapeutics SYRE Stock Holding History

Silverarc Capital Management’s Portfolio SYRE Stock Details SYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$5.32M Sell
59,959
-126,659
-68% -$9.24M 0.55% 50
2026
Q1 		$9.41M Sell
186,618
-1,119
-0.6% -$42.2K 0.96% 27
2025
Q4 		$6.15M Buy
+187,737
New +$4.91M 0.85% 31

Other funds holding SYRE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
VA
VR Adviser New York $3.3B AUM 525.74% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

Silverarc Capital Management's SYRE Position: Q2 2026 in Review

Silverarc Capital Management reduced its Spyre Therapeutics (SYRE) stake by 68% in Q2 2026, selling an estimated $9.24M and leaving 59,959 shares worth $5.32M. The position accounts for 0.55% of the portfolio, ranked #50.

Silverarc Capital Management first reported a position in SYRE in Q4 2025 and has held it in 3 quarters since. The position peaked at $9.41M in Q1 2026. 265 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • Silverarc Capital Management held 59,959 shares of Spyre Therapeutics worth $5.32M as of Q2 2026.
  • Silverarc Capital Management sold 126,659 Spyre Therapeutics shares in Q2 2026, an estimated $9.24M.
  • Spyre Therapeutics made up 0.55% of Silverarc Capital Management's portfolio in Q2 2026, its #50 holding.
  • Silverarc Capital Management first reported a position in Spyre Therapeutics in Q4 2025 and has held it in 3 quarters since.
  • Silverarc Capital Management's Spyre Therapeutics position peaked at $9.41M in Q1 2026.
  • 265 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on Silverarc Capital Management's 13F filing for Q2 2026, filed 13 Aug 2026.