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SAM

Sectoral Asset Management Portfolio holdings

AUM $121M
1-Year Est. Return 73.47%
This Fund
S&P 500
This Quarter Est. Return
-0.91%
1 Year Est. Return
+73.47%
3 Year Est. Return
+165.77%
5 Year Est. Return
+169.27%
10 Year Est. Return
+1,136.49%
AUM
$128M
AUM Growth
-$21.3M
Cap. Flow
-$12.5M
Cap. Flow %
-9.73%
Top 10 Hldgs %
52.36%
Holding
99
New
13
Increased
31
Reduced
37
Closed
15

Top Buys

Rank Stock Value
1
DXCM icon
DexCom
DXCM
+$1.22M
2
ISRG icon
Intuitive Surgical
ISRG
+$1.22M
3
THC icon
Tenet Healthcare
THC
+$1.19M
4
RDNT icon
RadNet
RDNT
+$1.18M
5
CVRX icon
CVRx
CVRX
+$967K

Top Sells

Rank Stock Value
1
LLY icon
Eli Lilly
LLY
+$2.6M
2
GILD icon
Gilead Sciences
GILD
+$1.99M
3
BMY icon
Bristol-Myers Squibb
BMY
+$1.43M
4
SRPT icon
Sarepta Therapeutics
SRPT
+$1.34M
5
HCAT icon
Health Catalyst
HCAT
+$1.13M

Sector Composition

Rank Sector Weight
1 Healthcare 99.72%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LENZ
1
LENZ Therapeutics
LENZ
$158M
$25.1M 19.56%
977,245
– –
LLY icon
2
Eli Lilly
LLY
$1.06T
$7.78M 6.05%
9,416
-3,130
-25% -$2.6M
UNH icon
3
UnitedHealth
UNH
$385B
$6.75M 5.26%
12,895
-1,730
-12% -$884K
MLYS icon
4
Mineralys Therapeutics
MLYS
$2.38B
$5.88M 4.58%
370,513
-10,370
-3% -$119K
CTNM
5
Contineum Therapeutics
CTNM
$537M
$5.59M 4.35%
800,787
– –
JNJ icon
6
Johnson & Johnson
JNJ
$624B
$3.62M 2.81%
21,800
-1,100
-5% -$172K
GILD icon
7
Gilead Sciences
GILD
$162B
$3.59M 2.79%
32,020
-19,290
-38% -$1.99M
AMGN icon
8
Amgen
AMGN
$201B
$3.24M 2.52%
10,385
-2,165
-17% -$639K
ABBV icon
9
AbbVie
ABBV
$454B
$3.1M 2.41%
14,800
-4,000
-21% -$778K
ISRG icon
10
Intuitive Surgical
ISRG
$119B
$2.6M 2.02%
5,250
+2,200
+72% +$1.22M
ABT icon
11
Abbott
ABT
$175B
$2.48M 1.93%
18,698
-5,700
-23% -$725K
BSX icon
12
Boston Scientific
BSX
$64.8B
$2.44M 1.9%
24,226
-8,300
-26% -$836K
MRK icon
13
Merck
MRK
$322B
$2.41M 1.88%
26,900
+2,400
+10% +$224K
VRTX icon
14
Vertex Pharmaceuticals
VRTX
$120B
$2.29M 1.78%
4,725
+1,055
+29% +$492K
SYK icon
15
Stryker
SYK
$122B
$2.27M 1.77%
6,100
-300
-5% -$114K
DHR icon
16
Danaher
DHR
$135B
$2.17M 1.69%
10,575
+3,300
+45% +$720K
MDT icon
17
Medtronic
MDT
$105B
$2.14M 1.67%
23,850
-2,500
-9% -$224K
ARGX icon
18
argenx
ARGX
$57.8B
$1.84M 1.43%
3,103
-327
-10% -$206K
REGN icon
19
Regeneron Pharmaceuticals
REGN
$68.3B
$1.76M 1.37%
2,773
-627
-18% -$431K
BMRN icon
20
BioMarin Pharmaceuticals
BMRN
$11.4B
$1.66M 1.29%
23,530
-5,870
-20% -$395K
TMO icon
21
Thermo Fisher Scientific
TMO
$213B
$1.62M 1.26%
3,250
-1,500
-32% -$812K
BNTX icon
22
BioNTech
BNTX
$23.3B
$1.56M 1.22%
17,175
-1,775
-9% -$199K
PFE icon
23
Pfizer
PFE
$143B
$1.51M 1.18%
59,650
-18,000
-23% -$471K
ALNY icon
24
Alnylam Pharmaceuticals
ALNY
$35.9B
$1.41M 1.09%
5,205
-3,095
-37% -$795K
AZN icon
25
AstraZeneca
AZN
$261B
$1.38M 1.07%
9,395
+2,070
+28% +$299K
1
2 3 4

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Sectoral Asset Management's Q1 2025 Portfolio in Review

As of Q1 2025, Sectoral Asset Management held 99 positions worth $128M, down 14% from $150M the previous quarter. Its ten largest holdings account for 52% of the portfolio.

Sectoral Asset Management withdrew a net $12.5M in Q1 2025, closing 15 positions and reducing 37 holdings. Its most notable exit was Sarepta Therapeutics, an estimated $1.34M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 99% a quarter earlier.

Against the trend, Sectoral Asset Management opened a new position in DexCom worth $1.02M.

  • Sectoral Asset Management's largest Q1 2025 buy was DexCom: 15,000 shares worth $1.02M.
  • Sectoral Asset Management added most to Intuitive Surgical in Q1 2025, an estimated $1.22M increase.
  • Sectoral Asset Management's biggest Q1 2025 reduction was Eli Lilly, cutting an estimated $2.6M.
  • Sectoral Asset Management fully exited Sarepta Therapeutics in Q1 2025, selling an estimated $1.34M.
  • Sectoral Asset Management's ten largest holdings make up 52% of its $128M portfolio in Q1 2025.
  • Sectoral Asset Management opened 13 new positions and closed 15 in Q1 2025.
  • Sectoral Asset Management's portfolio value fell 14% quarter-over-quarter to $128M.

Based on Sectoral Asset Management's 13F filing for Q1 2025, filed 15 May 2025.