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SAM

Sectoral Asset Management Portfolio holdings

AUM $121M
1-Year Est. Return 73.47%
This Fund
S&P 500
This Quarter Est. Return
+16.08%
1 Year Est. Return
+73.47%
3 Year Est. Return
+165.77%
5 Year Est. Return
+169.27%
10 Year Est. Return
+1,136.49%
AUM
$232M
AUM Growth
-$281M
Cap. Flow
-$304M
Cap. Flow %
-130.94%
Top 10 Hldgs %
35.11%
Holding
133
New
10
Increased
39
Reduced
47
Closed
29

Top Buys

Rank Stock Value
1
ARGX icon
argenx
ARGX
+$4.1M
2
SLRN
ACELYRIN
SLRN
+$2.78M
3
MRK icon
Merck
MRK
+$2.54M
4
EWTX icon
Edgewise Therapeutics
EWTX
+$2.3M
5
TVTX icon
Travere Therapeutics
TVTX
+$2M

Top Sells

Rank Stock Value
1
RCM
R1 RCM Inc. Common Stock
RCM
+$11.2M
2
BPMC
Blueprint Medicines
BPMC
+$10.6M
3
HQY icon
HealthEquity
HQY
+$10.5M
4
EVH icon
Evolent Health
EVH
+$10.4M
5
RDNT icon
RadNet
RDNT
+$10.4M

Sector Composition

Rank Sector Weight
1 Healthcare 99.21%
2 Industrials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LLY icon
1
Eli Lilly
LLY
$1.06T
$15.5M 6.67%
26,565
+3,300
+14% +$1.93M
UNH icon
2
UnitedHealth
UNH
$385B
$9.96M 4.29%
18,925
+2,000
+12% +$1.07M
MRK icon
3
Merck
MRK
$322B
$8.67M 3.73%
79,500
+24,500
+45% +$2.54M
JNJ icon
4
Johnson & Johnson
JNJ
$624B
$8.44M 3.63%
53,850
-3,000
-5% -$460K
AMGN icon
5
Amgen
AMGN
$201B
$8.26M 3.56%
28,685
+620
+2% +$169K
ABT icon
6
Abbott
ABT
$175B
$7.59M 3.27%
68,998
+16,500
+31% +$1.65M
ABBV icon
7
AbbVie
ABBV
$454B
$7.18M 3.09%
46,300
+7,000
+18% +$1.02M
PFE icon
8
Pfizer
PFE
$143B
$5.45M 2.35%
189,400
+32,000
+20% +$967K
BSX icon
9
Boston Scientific
BSX
$64.8B
$5.29M 2.28%
91,476
-7,500
-8% -$400K
MLYS icon
10
Mineralys Therapeutics
MLYS
$2.38B
$5.21M 2.24%
605,606
-235,153
-28% -$1.85M
BMRN icon
11
BioMarin Pharmaceuticals
BMRN
$11.4B
$4.83M 2.08%
50,070
-95,020
-65% -$8.41M
TMO icon
12
Thermo Fisher Scientific
TMO
$213B
$4.79M 2.06%
9,015
+1,850
+26% +$895K
ALNY icon
13
Alnylam Pharmaceuticals
ALNY
$35.9B
$4.33M 1.87%
22,640
-6,320
-22% -$1.08M
BIIB icon
14
Biogen
BIIB
$29.6B
$4.1M 1.76%
15,827
+815
+5% +$200K
IQV icon
15
IQVIA
IQV
$34.6B
$3.84M 1.65%
16,600
-2,400
-13% -$493K
ARGX icon
16
argenx
ARGX
$57.8B
$3.81M 1.64%
10,027
+8,800
+717% +$4.1M
HUM icon
17
Humana
HUM
$47.4B
$3.77M 1.62%
8,225
+900
+12% +$444K
VRTX icon
18
Vertex Pharmaceuticals
VRTX
$120B
$3.75M 1.62%
9,219
+450
+5% +$166K
DXCM icon
19
DexCom
DXCM
$27.2B
$3.65M 1.57%
29,400
-2,300
-7% -$235K
EWTX icon
20
Edgewise Therapeutics
EWTX
$4.23B
$3.59M 1.54%
+327,801
New +$2.3M
DHR icon
21
Danaher
DHR
$135B
$3.46M 1.49%
14,975
+2,595
+21% +$552K
REGN icon
22
Regeneron Pharmaceuticals
REGN
$68.3B
$3.37M 1.45%
3,835
+115
+3% +$94.7K
GILD icon
23
Gilead Sciences
GILD
$162B
$3.31M 1.43%
40,905
+2,755
+7% +$214K
MDT icon
24
Medtronic
MDT
$105B
$3.3M 1.42%
40,051
– –
ANNX icon
25
Annexon
ANNX
$868M
$2.96M 1.27%
650,911
-247,874
-28% -$613K
1
2 3 4 5

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Sectoral Asset Management's Q4 2023 Portfolio in Review

As of Q4 2023, Sectoral Asset Management held 133 positions worth $232M, down 55% from $514M the previous quarter. Its ten largest holdings account for 35% of the portfolio.

Sectoral Asset Management withdrew a net $304M in Q4 2023, closing 29 positions and reducing 47 holdings. Its most notable exit was R1 RCM Inc. Common Stock, an estimated $11.2M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 97% a quarter earlier, followed by Industrials.

Against the trend, Sectoral Asset Management opened a new position in ACELYRIN worth $2.43M.

  • Sectoral Asset Management's largest Q4 2023 buy was ACELYRIN: 325,549 shares worth $2.43M.
  • Sectoral Asset Management added most to argenx in Q4 2023, an estimated $4.1M increase.
  • Sectoral Asset Management's biggest Q4 2023 reduction was Blueprint Medicines, cutting an estimated $10.6M.
  • Sectoral Asset Management fully exited R1 RCM Inc. Common Stock in Q4 2023, selling an estimated $11.2M.
  • Sectoral Asset Management's ten largest holdings make up 35% of its $232M portfolio in Q4 2023.
  • Sectoral Asset Management opened 10 new positions and closed 29 in Q4 2023.
  • Sectoral Asset Management's portfolio value fell 55% quarter-over-quarter to $232M.

Based on Sectoral Asset Management's 13F filing for Q4 2023, filed 14 Feb 2024.