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SAM

Sectoral Asset Management Portfolio holdings

AUM $121M
1-Year Est. Return 73.47%
This Fund
S&P 500
This Quarter Est. Return
+6.83%
1 Year Est. Return
+73.47%
3 Year Est. Return
+165.77%
5 Year Est. Return
+169.27%
10 Year Est. Return
+1,136.49%
AUM
$1.32B
AUM Growth
-$100M
Cap. Flow
-$118M
Cap. Flow %
-8.94%
Top 10 Hldgs %
27.68%
Holding
135
New
38
Increased
26
Reduced
44
Closed
22

Top Buys

Rank Stock Value
1
OCDX
Ortho Clinical Diagnostics Holdings plc Ordinary Shares
OCDX
+$30.5M
2
ARQT icon
Arcutis Biotherapeutics
ARQT
+$27.4M
3
NVTA
Invitae Corporation
NVTA
+$26.1M
4
ACCD
Accolade Inc
ACCD
+$22.7M
5
VOR icon
Vor Biopharma
VOR
+$22.6M

Top Sells

Rank Stock Value
1
TNDM icon
Tandem Diabetes Care
TNDM
+$40.6M
2
ACAD icon
Acadia Pharmaceuticals
ACAD
+$35M
3
EXEL icon
Exelixis
EXEL
+$29.6M
4
LH icon
Labcorp
LH
+$28.8M
5
AFIB
Acutus Medical Inc
AFIB
+$28.3M

Sector Composition

Rank Sector Weight
1 Healthcare 93.61%
2 Industrials 3.88%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARGX icon
101
argenx
ARGX
$51.8B
$515K 0.04%
1,870
-630
-25% -$199K
KLRS
102
Kalaris Therapeutics
KLRS
$89M
$502K 0.04%
933
+509
+120% +$428K
OLMA icon
103
Olema Pharmaceuticals
OLMA
$983M
$428K 0.03%
+12,900
New +$553K
ALGS icon
104
Aligos Therapeutics
ALGS
$28.3M
$425K 0.03%
748
– –
ASND icon
105
Ascendis Pharma A/S
ASND
$16B
$419K 0.03%
+3,250
New +$494K
CRSP icon
106
CRISPR Therapeutics
CRSP
$4.84B
$398K 0.03%
3,270
-21,700
-87% -$3.28M
RDY icon
107
Dr. Reddy's Laboratories
RDY
$10B
$396K 0.03%
32,270
– –
RPTX
108
DELISTED
Repare Therapeutics
RPTX
$307K 0.02%
+10,000
New +$340K
LEGN icon
109
Legend Biotech
LEGN
$3.66B
$299K 0.02%
+10,300
New +$281K
COGT icon
110
Cogent Biosciences
COGT
$6.66B
$237K 0.02%
+27,000
New +$260K
GTH
111
DELISTED
Genetron Holdings Limited ADS
GTH
$232K 0.02%
+3,600
New +$247K
DNLI icon
112
Denali Therapeutics
DNLI
$3.66B
$228K 0.02%
+4,000
New +$268K
AVEO
113
DELISTED
AVEO Pharmaceuticals, Inc.
AVEO
$185K 0.01%
25,300
-1,125,875
-98% -$9.71M
ACAD icon
114
Acadia Pharmaceuticals
ACAD
$4.38B
– –
-654,414
Closed -$35M
AMWL icon
115
American Well
AMWL
$182M
– –
-36,206
Closed -$18.3M
APLS
116
DELISTED
Apellis Pharmaceuticals
APLS
– –
-65,000
Closed -$3.72M
APRE icon
117
Aprea Therapeutics
APRE
$7.43M
– –
-8,184
Closed -$805K
BPMC
118
DELISTED
Blueprint Medicines
BPMC
– –
-136,500
Closed -$15.3M
CERT icon
119
Certara
CERT
$1.28B
– –
-605,900
Closed -$20.4M
FDMT icon
120
4D Molecular Therapeutics
FDMT
$518M
– –
-5,224
Closed -$217K
KYNB
121
Kyntra Bio
KYNB
$28.3M
– –
-4,160
Closed -$3.86M
IDXX icon
122
Idexx Laboratories
IDXX
$44.7B
– –
-47,399
Closed -$23.7M
IRTC icon
123
iRhythm Holdings
IRTC
$4.04B
– –
-106,565
Closed -$25.3M
KOD icon
124
Kodiak Sciences
KOD
$2.61B
– –
-1,650
Closed -$242K
MRK icon
125
Merck
MRK
$314B
– –
-46,636
Closed -$3.64M
2 3 4
5
6

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Sectoral Asset Management's Q1 2021 Portfolio in Review

As of Q1 2021, Sectoral Asset Management held 135 positions worth $1.32B, down 7% from $1.42B the previous quarter. Its ten largest holdings account for 28% of the portfolio.

Sectoral Asset Management withdrew a net $118M in Q1 2021, closing 22 positions and reducing 44 holdings. Its most notable exit was Acadia Pharmaceuticals, an estimated $35M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, down from 97% a quarter earlier, followed by Industrials.

Against the trend, Sectoral Asset Management opened a new position in Ortho Clinical Diagnostics Holdings plc Ordinary Shares worth $33.4M.

  • Sectoral Asset Management's largest Q1 2021 buy was Ortho Clinical Diagnostics Holdings plc Ordinary Shares: 1,730,500 shares worth $33.4M.
  • Sectoral Asset Management added most to TG Therapeutics in Q1 2021, an estimated $14.8M increase.
  • Sectoral Asset Management's biggest Q1 2021 reduction was Tandem Diabetes Care, cutting an estimated $40.6M.
  • Sectoral Asset Management fully exited Acadia Pharmaceuticals in Q1 2021, selling an estimated $35M.
  • Sectoral Asset Management's ten largest holdings make up 28% of its $1.32B portfolio in Q1 2021.
  • Sectoral Asset Management opened 38 new positions and closed 22 in Q1 2021.
  • Sectoral Asset Management's portfolio value fell 7% quarter-over-quarter to $1.32B.

Based on Sectoral Asset Management's 13F filing for Q1 2021, filed 14 May 2021.