Renaissance Technologies
DRRX

Renaissance Technologies’s DURECT Corp DRRX Stock Holding History

Renaissance Technologies’s Portfolio DRRX Stock Details DRRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-177,766
Closed -$113K – 3590
2025
Q2 		$113K Buy
177,766
+5,300
+3% +$3.42K ﹤0.01% 3281
2025
Q1 		$138K Buy
172,466
+3,700
+2% +$2.97K ﹤0.01% 3143
2024
Q4 		$127K Hold
168,766
– – ﹤0.01% 3250
2024
Q3 		$226K Buy
168,766
+500
+0.3% +$711 ﹤0.01% 3084
2024
Q2 		$217K Buy
168,266
+2,300
+1% +$2.71K ﹤0.01% 3019
2024
Q1 		$201K Sell
165,966
-20,200
-11% -$18.4K ﹤0.01% 3229
2023
Q4 		$110K Sell
186,166
-106,500
-36% -$152K ﹤0.01% 3283
2023
Q3 		$729K Sell
292,666
-69,860
-19% -$238K ﹤0.01% 2510
2023
Q2 		$1.79M Buy
362,526
+87,860
+32% +$445K ﹤0.01% 2069
2023
Q1 		$1.24M Sell
274,666
-13,820
-5% -$75K ﹤0.01% 2331
2022
Q4 		$998K Sell
288,486
-56,238
-16% -$267K ﹤0.01% 2532
2022
Q3 		$1.99M Buy
344,724
+10,340
+3% +$63K ﹤0.01% 2004
2022
Q2 		$1.6M Sell
334,384
-15,644
-4% -$74.7K ﹤0.01% 2360
2022
Q1 		$2.35M Buy
350,028
+58,885
+20% +$409K ﹤0.01% 2124
2021
Q4 		$2.87M Sell
291,143
-7,450
-2% -$82.3K ﹤0.01% 1875
2021
Q3 		$3.82M Sell
298,593
-18,280
-6% -$248K ﹤0.01% 1622
2021
Q2 		$5.17M Sell
316,873
-73,317
-19% -$1.28M 0.01% 1613
2021
Q1 		$7.73M Sell
390,190
-87,503
-18% -$1.97M 0.01% 1359
2020
Q4 		$9.89M Sell
477,693
-52,840
-10% -$1.01M 0.01% 1181
2020
Q3 		$9.07M Sell
530,533
-68,437
-11% -$1.37M 0.01% 1210
2020
Q2 		$13.9M Buy
598,970
+78,149
+15% +$1.72M 0.01% 1028
2020
Q1 		$8.07M Buy
520,821
+98,900
+23% +$1.9M 0.01% 1293
2019
Q4 		$16M Buy
421,921
+20,769
+5% +$428K 0.01% 1132
2019
Q3 		$7.38M Buy
401,152
+80,363
+25% +$1.09M 0.01% 1585
2019
Q2 		$2.09M Buy
320,789
+16,180
+5% +$101K ﹤0.01% 2301
2019
Q1 		$1.91M Sell
304,609
-29,280
-9% -$198K ﹤0.01% 2326
2018
Q4 		$1.61M Buy
333,889
+2,459
+0.7% +$21.5K ﹤0.01% 2344
2018
Q3 		$3.65M Buy
331,430
+4,481
+1% +$60.9K ﹤0.01% 1985
2018
Q2 		$5.1M Buy
326,949
+150,489
+85% +$3.09M 0.01% 1776
2018
Q1 		$3.78M Buy
176,460
+108,320
+159% +$1.51M ﹤0.01% 2001
2017
Q4 		$628K Buy
68,140
+58,270
+590% +$693K ﹤0.01% 2831
2017
Q3 		$175K Buy
9,870
+2,530
+34% +$42.4K ﹤0.01% 3026
2017
Q2 		$115K Buy
+7,340
New +$83.6K ﹤0.01% 3075
2016
Q1 		– Sell
-13,900
Closed -$307K – 3402
2015
Q4 		$307K Sell
13,900
-6,780
-33% -$147K ﹤0.01% 2879
2015
Q3 		$403K Sell
20,680
-2,030
-9% -$46.2K ﹤0.01% 2688
2015
Q2 		$543K Buy
22,710
+16,840
+287% +$396K ﹤0.01% 2698
2015
Q1 		$112K Buy
5,870
+4,090
+230% +$48.6K ﹤0.01% 2995
2014
Q4 		$14K Sell
1,780
-940
-35% -$9.17K ﹤0.01% 2928
2014
Q3 		$40K Buy
+2,720
New +$42.2K ﹤0.01% 2721
2014
Q1 		– Sell
-4,105
Closed -$71K – 2877
2013
Q4 		$71K Buy
+4,105
New +$62.1K ﹤0.01% 2764

Other funds holding DRRX

IA
IFP Advisors Tampa, Florida $5.54B AUM 27.43% 1-Year Est. Return
Osaic Holdings
Osaic Holdings Scottsdale, Arizona $68.3B AUM 20.5% 1-Year Est. Return

Renaissance Technologies's DRRX Position: Q3 2025 in Review

Renaissance Technologies sold out of DURECT Corp (DRRX) in Q3 2025, closing a stake of 177,766 shares — an estimated $113K sold.

Renaissance Technologies first reported a position in DRRX in Q4 2013 and held it in 40 quarters. The position peaked at $16M in Q4 2019. 2 funds tracked by Wall St. Rank hold DRRX as of Q3 2025.

  • Renaissance Technologies reported no remaining DURECT Corp position as of Q3 2025 after selling out during the quarter.
  • Renaissance Technologies sold 177,766 DURECT Corp shares in Q3 2025, an estimated $113K.
  • Renaissance Technologies first reported a position in DURECT Corp in Q4 2013 and held it in 40 quarters.
  • Renaissance Technologies's DURECT Corp position peaked at $16M in Q4 2019.
  • 2 funds tracked by Wall St. Rank held DURECT Corp as of Q3 2025.

Based on Renaissance Technologies's 13F filing for Q3 2025, filed 13 Nov 2025.