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DRRX

DURECT Corp

Delisted

DRRX was delisted on the 10th of September, 2025.

101 hedge funds and large institutions have $113M invested in DURECT Corp in 2021 Q4 according to their latest regulatory filings, with 13 funds opening new positions, 30 increasing their positions, 35 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,843% more call options, than puts

Call options by funds: $206K | Put options by funds: $7K

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

0.02% less ownership

Funds ownership: 5.09%5.06% (-0.02%)

8% less funds holding

Funds holding: 110101 (-9)

14% less repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 35

23% less capital invested

Capital invested by funds: $148M → $113M (-$34.7M)

38% less first-time investments, than exits

New positions opened: 13 | Existing positions closed: 21

Holders
101
Holders Change
-9
Holders Change %
-8.18%
% of All Funds
1.55%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
13
Increased
30
Reduced
35
Closed
21
Calls
$206K
Puts
$7K
Net Calls
+$199K
Net Calls Change
-$229K
Name Holding Trade Value Shares
Change
Change in
Stake
BL
1
Bleichroeder LP
New York
$26M
LPC
2
Lion Point Capital
New York
$15.3M
BlackRock
3
BlackRock
New York
$13.7M -$447K -40,432 -3%
Vanguard Group
4
Vanguard Group
Pennsylvania
$11.1M -$142K -12,818 -1%
ISL
5
Ingalls & Snyder LLC
New York
$7.2M +$3.2K +290 +0%
AC
6
Antara Capital
New York
$4.32M +$1.23M +111,715 +34%
State Street
7
State Street
Massachusetts
$3.87M -$473K -42,831 -10%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$3.79M -$25.6K -2,319 -0.6%
CM
9
CM Management
Florida
$2.88M +$304K +27,520 +10%
Renaissance Technologies
10
Renaissance Technologies
New York
$2.87M -$82.3K -7,450 -2%
JP Morgan Chase
11
JP Morgan Chase
New York
$2.79M -$105K -9,465 -3%
BWCS
12
Beirne Wealth Consulting Services
Connecticut
$2.47M +$159K +14,386 +6%
Northern Trust
13
Northern Trust
Illinois
$2.05M -$396K -35,819 -15%
GS
14
Gagnon Securities
New York
$1.38M +$81.4K +7,365 +6%
HFA
15
Harbert Fund Advisors
Alabama
$1.25M
TAM
16
Tocqueville Asset Management
New York
$889K +$33K +2,990 +3%
JG
17
Jefferies Group
New York
$839K
IIM
18
Ironwood Investment Management
Massachusetts
$821K -$8.27K -749 -0.9%
Millennium Management
19
Millennium Management
New York
$812K +$763K +69,110 +521%
KPCM
20
Kings Point Capital Management
New York
$809K
N
21
Nuveen
North Carolina
$757K -$83.5K -7,562 -8%
Bank of New York Mellon
22
Bank of New York Mellon
New York
$672K +$13.5K +1,221 +2%
Charles Schwab
23
Charles Schwab
California
$586K
Two Sigma Advisers
24
Two Sigma Advisers
New York
$485K +$60.6K +5,490 +13%
Dimensional Fund Advisors
25
Dimensional Fund Advisors
Texas
$273K -$54.2K -4,903 -15%

DRRX Hedge Fund Activity: Q4 2021 in Review

101 of the 6,499 institutional investors tracked by Wall St. Rank reported a position in DURECT Corp (DRRX) for Q4 2021, worth a combined $113M — down 23% from $148M a quarter earlier.

Sellers outnumbered buyers: 21 funds closed out of DRRX and 13 opened new positions — a net loss of 8 holders — while 35 trimmed existing stakes and 30 added.

The largest buyer was Antara Capital, adding an estimated $1.23M. The largest seller was Swiss National Bank, exiting entirely with an estimated $643K sold.

  • 101 institutional investors held DURECT Corp (DRRX) as of Q4 2021, down from 110 in Q3 2021.
  • Funds reported $113M of DURECT Corp stock for Q4 2021, down 23% quarter-over-quarter.
  • 13 funds opened new DURECT Corp positions in Q4 2021 and 21 closed out, a net change of -8 holders.
  • The largest DURECT Corp buyer in Q4 2021 was Antara Capital, an estimated $1.23M added.
  • The largest DURECT Corp seller in Q4 2021 was Swiss National Bank, an estimated $643K sold.

Based on aggregated 13F filings for Q4 2021.