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DRRX

DURECT Corp
DRRX

Delisted

DRRX was delisted on the 10th of September, 2025.

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77 hedge funds and large institutions have $349M invested in DURECT Corp in 2019 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 31 increasing their positions, 14 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

229% more capital invested

Capital invested by funds: $106M → $349M (+$243M)

121% more repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 14

100% more funds holding in top 10

Funds holding in top 10: 2 → 4 (+2)

36% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 11

11% more call options, than puts

Call options by funds: $3.96M | Put options by funds: $3.57M

5% more funds holding

Funds holding: 73 → 77 (+4)

1.75% more ownership

Funds ownership: 3.02% → 4.78% (+1.8%)

Holders
77
Holders Change
+4
Holders Change %
+5.48%
% of All Funds
1.52%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.08%
New
15
Increased
31
Reduced
14
Closed
11
Calls
$3.96M
Puts
$3.57M
Net Calls
+$391K
Net Calls Change
+$527K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$5.8M
2
DC
Davenport & Co
Virginia
+$2.18M
3
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$1.52M
4
Two Sigma Investments
Two Sigma Investments
New York
+$1.16M
5
Vanguard Group
Vanguard Group
Pennsylvania
+$1.11M

Top Sellers

Rank Fund Capital Flow
1
ISL
Ingalls & Snyder LLC
New York
-$793K
2
OAM
Oxford Asset Management
United Kingdom
-$728K
3
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
-$692K
4
WG
Winton Group
United Kingdom
-$503K
5
PP
Paloma Partners
Connecticut
-$436K
Name Holding Trade Value Shares
Change 		Change in
Stake
BL
1
Bleichroeder LP
New York
$101M +$54.6M +2,647,655 New
LPC
2
Lion Point Capital
New York
$71.3M – – –
Vanguard Group
3
Vanguard Group
Pennsylvania
$31.2M +$1.11M +53,869 +7%
ISL
4
Ingalls & Snyder LLC
New York
$29.7M -$793K -38,480 -5%
Renaissance Technologies
5
Renaissance Technologies
New York
$16M +$428K +20,769 +5%
BlackRock
6
BlackRock
New York
$13.7M +$576K +27,969 +8%
Millennium Management
7
Millennium Management
New York
$12.7M +$5.8M +281,637 +545%
BWCS
8
Beirne Wealth Consulting Services
Connecticut
$6.29M +$253K +12,274 +8%
DC
9
Davenport & Co
Virginia
$6.26M +$2.18M +105,654 +179%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$5.78M +$127K +6,146 +4%
GS
11
Gagnon Securities
New York
$4.43M -$117K -5,686 -5%
KPCM
12
Kings Point Capital Management
New York
$4.39M – – –
Acadian Asset Management
13
Acadian Asset Management
Massachusetts
$4.32M +$19.3K +937 +0.8%
TAM
14
Tocqueville Asset Management
New York
$4.3M +$7.63K +370 +0.3%
IIM
15
Ironwood Investment Management
Massachusetts
$3.5M +$48.9K +2,372 +3%
Two Sigma Investments
16
Two Sigma Investments
New York
$3.11M +$1.16M +56,071 +218%
Susquehanna International Group
17
Susquehanna International Group
Pennsylvania
$3.02M +$1.52M +73,592 +1,247%
PAM
18
Panagora Asset Management
Massachusetts
$2.6M +$223K +10,806 +19%
EGI
19
EAM Global Investors
California
$1.92M +$1.04M +50,397 New
ECM
20
ExodusPoint Capital Management
New York
$1.77M +$759K +36,821 +382%
Two Sigma Advisers
21
Two Sigma Advisers
New York
$1.7M +$837K +40,600 +995%
California Public Employees Retirement System
22
California Public Employees Retirement System
California
$1.56M +$200K +9,703 +31%
Northern Trust
23
Northern Trust
Illinois
$1.51M +$16K +777 +2%
EI
24
EAM Investors
California
$1.48M +$803K +38,967 New
RJA
25
Raymond James & Associates
Florida
$1.45M +$78.3K +3,800 +11%
1
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DRRX Hedge Fund Activity: Q4 2019 in Review

77 of the 5,076 institutional investors tracked by Wall St. Rank reported a position in DURECT Corp (DRRX) for Q4 2019, worth a combined $349M — up 229% from $106M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new DRRX positions and 11 closed out — a net gain of 4 holders — while 31 added to existing stakes and 14 trimmed.

The largest buyer was Millennium Management, adding an estimated $5.8M. The largest seller was Ingalls & Snyder LLC, cutting an estimated $793K.

  • 77 institutional investors held DURECT Corp (DRRX) as of Q4 2019, up from 73 in Q3 2019.
  • Funds reported $349M of DURECT Corp stock for Q4 2019, up 229% quarter-over-quarter.
  • 15 funds opened new DURECT Corp positions in Q4 2019 and 11 closed out, a net change of +4 holders.
  • The largest DURECT Corp buyer in Q4 2019 was Millennium Management, an estimated $5.8M added.
  • The largest DURECT Corp seller in Q4 2019 was Ingalls & Snyder LLC, an estimated $793K sold.

Based on aggregated 13F filings for Q4 2019.