OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+14.09%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$328M
AUM Growth
+$328M
Cap. Flow
-$47.8M
Cap. Flow %
-14.57%
Top 10 Hldgs %
48.5%
Holding
63
New
10
Increased
14
Reduced
12
Closed
20

Top Buys

1
LXRX icon
Lexicon Pharmaceuticals
LXRX
$9.31M
2
BHVN
Biohaven Pharmaceutical Holding Company Ltd.
BHVN
$6.57M
3
IRWD icon
Ironwood Pharmaceuticals
IRWD
$5.75M
4
ARVN icon
Arvinas
ARVN
$4.84M
5
OCUL icon
Ocular Therapeutix
OCUL
$4.62M

Top Sells

1
ASND icon
Ascendis Pharma
ASND
$11.2M
2
CMTA
Clementia Pharmaceuticals Inc.
CMTA
$10.4M
3
NVTA
Invitae Corporation
NVTA
$10.3M
4
CPRX icon
Catalyst Pharmaceutical
CPRX
$9.31M
5
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$7.7M

Sector Composition

1 Healthcare 98.09%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
TVTX icon
51
Travere Therapeutics
TVTX
$1.75B
– –
-205,000
Closed -$4.64M
TVRD
52
Tvardi Therapeutics, Inc. Common Stock
TVRD
$270M
– –
-5,556
Closed -$3.92M
SWAV
53
DELISTED
Shockwave Medical, Inc. Common Stock
SWAV
– –
-92,100
Closed -$3.08M
CBAY
54
DELISTED
Cymabay Therapeutics
CBAY
– –
-550,000
Closed -$7.3M
NVTA
55
DELISTED
Invitae Corporation
NVTA
– –
-440,000
Closed -$10.3M
MRTX
56
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
– –
-105,000
Closed -$7.7M
ACOR
57
DELISTED
Acorda Therapeutics, Inc.
ACOR
– –
-2,208
Closed -$3.52M
FOMX
58
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
– –
-180,000
Closed -$675K
DERM
59
DELISTED
Dermira, Inc.
DERM
– –
-400,000
Closed -$5.42M
HZNP
60
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
– –
-185,000
Closed -$4.89M
CMTA
61
DELISTED
Clementia Pharmaceuticals Inc.
CMTA
– –
-400,130
Closed -$10.4M
LJPC
62
DELISTED
La Jolla Pharmaceutical Company
LJPC
– –
-60,000
Closed -$386K
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