OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
-1.06%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$471M
AUM Growth
+$471M
Cap. Flow
-$18.7M
Cap. Flow %
-3.96%
Top 10 Hldgs %
58.75%
Holding
54
New
6
Increased
11
Reduced
10
Closed
15

Top Buys

1
CRNX icon
Crinetics Pharmaceuticals
CRNX
$9.16M
2
RETA
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
$8.7M
3
DNA icon
Ginkgo Bioworks
DNA
$7.73M
4
MRUS icon
Merus
MRUS
$6.92M
5
HYPR icon
Hyperfine
HYPR
$5.52M

Top Sells

1
ADMS
Adamas Pharmaceuticals, Inc.
ADMS
$7.17M
2
DCPH
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$6.98M
3
CLDX icon
Celldex Therapeutics
CLDX
$5.45M
4
AFIB
Acutus Medical, Inc. Common Stock
AFIB
$5.22M
5
KROS icon
Keros Therapeutics
KROS
$5.08M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
TELA icon
26
TELA Bio
TELA
$65.4M
$5.76M 1.22%
449,867
+6,668
+2% +$85.3K
HYPR icon
27
Hyperfine
HYPR
$88M
$5.52M 1.17%
+763,075
New +$5.52M
BBIO icon
28
BridgeBio Pharma
BBIO
$9.91B
$5.47M 1.16%
328,100
-183,400
-36% -$3.06M
NGNE icon
29
Neurogene
NGNE
$284M
$5.05M 1.07%
52,365
– –
FDMT icon
30
4D Molecular Therapeutics
FDMT
$302M
$5.02M 1.07%
+229,000
New +$5.02M
VSTM icon
31
Verastem
VSTM
$585M
$4.77M 1.01%
193,750
– –
SRRA
32
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$3.6M 0.76%
165,778
– –
MEIP icon
33
MEI Pharma
MEIP
$149M
$3.51M 0.74%
65,750
-12,500
-16% -$667K
NCNA
34
NuCana
NCNA
$5.8M
$2.83M 0.6%
238
+142
+148% +$1.69M
AVTX icon
35
Avalo Therapeutics
AVTX
$139M
$2.48M 0.53%
507
– –
SYBX icon
36
Synlogic
SYBX
$17.4M
$2.06M 0.44%
+56,667
New +$2.06M
AVEO
37
DELISTED
AVEO Pharmaceuticals, Inc.
AVEO
$1.24M 0.26%
263,400
-192,200
-42% -$901K
LQDA icon
38
Liquidia Corp
LQDA
$2.52B
$82K 0.02%
+16,800
New +$82K
BLRX
39
BioLineRX
BLRX
$15.5M
$34K 0.01%
417
– –
AKBA icon
40
Akebia Therapeutics
AKBA
$827M
– –
-311,300
Closed -$897K
DTIL icon
41
Precision BioSciences
DTIL
$59.5M
– –
-5,463
Closed -$1.89M
FOLD icon
42
Amicus Therapeutics
FOLD
$2.42B
– –
-320,800
Closed -$3.06M
LPTX icon
43
Leap Therapeutics
LPTX
$12M
– –
-47,600
Closed -$1.91M
OPTN
44
DELISTED
OptiNose
OPTN
– –
-103,900
Closed -$4.68M
RNAC icon
45
Cartesian Therapeutics
RNAC
$267M
– –
-3,533
Closed -$441K
WHWK
46
Whitehawk Therapeutics, Inc. Common Stock
WHWK
$85.3M
– –
-45,020
Closed -$1.32M
VIRX
47
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
– –
-258,556
Closed -$2.07M
DCPH
48
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
– –
-205,381
Closed -$6.98M
AFIB
49
DELISTED
Acutus Medical, Inc. Common Stock
AFIB
– –
-590,000
Closed -$5.22M
CBAY
50
DELISTED
Cymabay Therapeutics
CBAY
– –
-115,015
Closed -$420K
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