OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
-2.21%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$170M
AUM Growth
+$170M
Cap. Flow
-$12M
Cap. Flow %
-7.07%
Top 10 Hldgs %
56.85%
Holding
56
New
12
Increased
10
Reduced
12
Closed
16

Top Buys

1
TBPH icon
Theravance Biopharma
TBPH
$5.04M
2
MNTA
Momenta Pharmaceuticals, Inc.
MNTA
$4.97M
3
ENTA icon
Enanta Pharmaceuticals
ENTA
$3.02M
4
SBBP
Strongbridge Biopharma plc.
SBBP
$2.78M
5
BPMC
Blueprint Medicines
BPMC
$2.66M

Top Sells

1
CYNA
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR (CANADA)
CYNA
$5.03M
2
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$4.99M
3
GBT
Global Blood Therapeutics, Inc.
GBT
$4.61M
4
IMMU
Immunomedics Inc
IMMU
$3.9M
5
ZGNX
Zogenix, Inc.
ZGNX
$2.52M

Sector Composition

1 Healthcare 95.63%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ABEO icon
26
Abeona Therapeutics
ABEO
$356M
$1.94M 1.14%
400,000
+300,000
+300% +$1.46M
CTMX icon
27
CytomX Therapeutics
CTMX
$350M
$1.87M 1.1%
170,000
+10,000
+6% +$110K
KA
28
DELISTED
Kineta, Inc. Common Stock
KA
$1.84M 1.08%
150,000
-2,000
-1% -$25.8K
HROW icon
29
Harrow
HROW
$1.38B
$1.8M 1.06%
720,000
-495,381
-41% -$1.24M
SAGE
30
DELISTED
Sage Therapeutics
SAGE
$1.79M 1.05%
+35,000
New +$1.79M
NDRM
31
DELISTED
NeuroDerm Ltd. Ordinary Shares
NDRM
$1.73M 1.02%
115,000
+16,500
+17% +$248K
WGBS
32
DELISTED
WaferGen Bio-systems, Inc.
WGBS
$1.58M 0.93%
+320,000
New +$1.58M
CORI
33
DELISTED
Corium International, Inc.
CORI
$1.54M 0.91%
380,000
-20,000
-5% -$81.2K
SGMO icon
34
Sangamo Therapeutics
SGMO
$161M
$1.22M 0.72%
+400,000
New +$1.22M
AKAO
35
DELISTED
Achaogen, Inc.
AKAO
$1.04M 0.61%
+80,000
New +$1.04M
OCUL icon
36
Ocular Therapeutix
OCUL
$2.25B
$783K 0.46%
+93,600
New +$783K
TRIL
37
DELISTED
Trillium Therapeutics Inc.
TRIL
$622K 0.37%
110,000
-65,000
-37% -$368K
BLRX
38
BioLineRX
BLRX
$15.5M
$230K 0.14%
250,000
– –
AGRX
39
DELISTED
Agile Therapeutics, Inc
AGRX
$85K 0.05%
+15,000
New +$85K
INNL
40
DELISTED
Innocoll Holdings plc Ordinary Shares
INNL
– –
-269,100
Closed -$1.56M
HZNP
41
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
– –
-275,000
Closed -$4.99M
PTLA
42
DELISTED
Portola Pharmaceuticals, Inc.
PTLA
– –
-35,000
Closed -$795K
ASRT icon
43
Assertio
ASRT
$78M
– –
-1,650
Closed -$41K
AMRN
44
Amarin Corp
AMRN
$311M
– –
-700,000
Closed -$2.23M
AFMD
45
DELISTED
Affimed
AFMD
– –
-430,000
Closed -$1.2M
ZGNX
46
DELISTED
Zogenix, Inc.
ZGNX
– –
-220,000
Closed -$2.52M
CYNA
47
DELISTED
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR (CANADA)
CYNA
– –
-125,000
Closed -$5.03M
INDP icon
48
Indaptus Therapeutics
INDP
$5.98M
– –
-175,000
Closed -$1.03M
RARE icon
49
Ultragenyx Pharmaceutical
RARE
$3.04B
– –
-35,000
Closed -$2.48M
TENX icon
50
Tenax Therapeutics
TENX
$27.5M
– –
-390,000
Closed -$905K
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