OM

Opaleye Management Portfolio holdings

AUM $494M
1-Year Return 68.17%
This Quarter Return
+39.37%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$191M
AUM Growth
+$41.4M
Cap. Flow
-$2.25M
Cap. Flow %
-1.18%
Top 10 Hldgs %
52.91%
Holding
54
New
5
Increased
14
Reduced
20
Closed
9

Top Buys

1
BPMC
Blueprint Medicines
BPMC
$15.9M
2
PRTA icon
Prothena Corp
PRTA
$3M
3
LOXO
Loxo Oncology, Inc
LOXO
$2.88M
4
AGIO icon
Agios Pharmaceuticals
AGIO
$2.38M
5
EGRX
Eagle Pharmaceuticals, Inc.
EGRX
$1.4M

Top Sells

1
AMRN
Amarin Corp
AMRN
$3.38M
2
ARIA
Ariad Pharmaceuticals Inc
ARIA
$2.81M
3
INDP icon
Indaptus Therapeutics
INDP
$2.8M
4
AMAG
AMAG Pharmaceuticals, Inc.
AMAG
$2.58M
5
SUPN icon
Supernus Pharmaceuticals
SUPN
$2.55M

Sector Composition

1 Healthcare 86.83%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
CTMX icon
26
CytomX Therapeutics
CTMX
$346M
$2.51M 1.31%
160,000
– –
RARE icon
27
Ultragenyx Pharmaceutical
RARE
$3.01B
$2.48M 1.3%
35,000
-30,000
-46% -$2.13M
KA
28
DELISTED
Kineta, Inc. Common Stock
KA
$2.37M 1.24%
1,086
+336
+45% +$733K
IOVA icon
29
Iovance Biotherapeutics
IOVA
$796M
$2.3M 1.21%
280,000
+20,000
+8% +$165K
CORI
30
DELISTED
Corium International, Inc.
CORI
$2.25M 1.18%
400,000
+40,000
+11% +$225K
AMRN
31
Amarin Corp
AMRN
$311M
$2.23M 1.17%
35,000
-53,000
-60% -$3.38M
NDRM
32
DELISTED
NeuroDerm Ltd. Ordinary Shares
NDRM
$1.82M 0.95%
98,500
+46,000
+88% +$850K
NBRV
33
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$1.69M 0.88%
958
-122
-11% -$215K
INNL
34
DELISTED
Innocoll Holdings plc Ordinary Shares
INNL
$1.56M 0.82%
269,100
+4,100
+2% +$23.8K
AFMD
35
DELISTED
Affimed
AFMD
$1.2M 0.63%
43,000
-16,500
-28% -$459K
INDP icon
36
Indaptus Therapeutics
INDP
$5.1M
$1.03M 0.54%
78
-212
-73% -$2.8M
TENX icon
37
Tenax Therapeutics
TENX
$27.4M
$905K 0.47%
12
-3
-20% -$226K
PTLA
38
DELISTED
Portola Pharmaceuticals, Inc.
PTLA
$795K 0.42%
+35,000
New +$795K
ABEO icon
39
Abeona Therapeutics
ABEO
$352M
$600K 0.31%
+4,000
New +$600K
AMAG
40
DELISTED
AMAG Pharmaceuticals, Inc.
AMAG
$368K 0.19%
15,000
-105,000
-88% -$2.58M
BLRX
41
BioLineRX
BLRX
$15.1M
$288K 0.15%
417
– –
ASRT icon
42
Assertio
ASRT
$77.7M
$41K 0.02%
+413
New +$41K
ADAP
43
Adaptimmune Therapeutics
ADAP
$13.5M
– –
-40,000
Closed -$326K
CDTX icon
44
Cidara Therapeutics
CDTX
$1.65B
– –
-2,150
Closed -$443K
EVOK icon
45
Evoke Pharma
EVOK
$8.24M
– –
-903
Closed -$891K
MCRB icon
46
Seres Therapeutics
MCRB
$165M
– –
-2,875
Closed -$1.67M
OCUL icon
47
Ocular Therapeutix
OCUL
$2.21B
– –
-260,000
Closed -$1.29M
SUPN icon
48
Supernus Pharmaceuticals
SUPN
$2.55B
– –
-125,000
Closed -$2.55M
TGTX icon
49
TG Therapeutics
TGTX
$5.06B
– –
-175,000
Closed -$1.06M
TNXP icon
50
Tonix Pharmaceuticals
TNXP
$231M
– –
0
– -$1.59M
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