Millennium Management
PYXS icon

Millennium Management’s Pyxis Oncology PYXS Stock Holding History

Millennium Management’s Portfolio PYXS Stock Details PYXS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$581K Sell
397,625
-345,482
-46% -$521K ﹤0.01% 4685
2025
Q4 		$855K Sell
743,107
-72,224
-9% -$255K ﹤0.01% 4590
2025
Q3 		$1.81M Sell
815,331
-2,724,529
-77% -$3.92M ﹤0.01% 4148
2025
Q2 		$3.89M Buy
3,539,860
+1,054,584
+42% +$1.19M ﹤0.01% 3244
2025
Q1 		$2.44M Sell
2,485,276
-495,630
-17% -$661K ﹤0.01% 3595
2024
Q4 		$4.65M Buy
2,980,906
+1,073,928
+56% +$3.1M ﹤0.01% 2877
2024
Q3 		$7M Buy
1,906,978
+570,070
+43% +$1.99M ﹤0.01% 2531
2024
Q2 		$4.43M Buy
1,336,908
+753,899
+129% +$3.17M ﹤0.01% 2834
2024
Q1 		$2.48M Buy
583,009
+569,737
+4,293% +$2.4M ﹤0.01% 3530
2023
Q4 		$23.9K Buy
+13,272
New +$22.7K ﹤0.01% 5604
2023
Q3 		– Sell
-30,878
Closed -$79K – 6469
2023
Q2 		$79K Buy
+30,878
New +$97.9K ﹤0.01% 5377
2023
Q1 		– Sell
-31,334
Closed -$42K – 6756
2022
Q4 		$42K Sell
31,334
-58,504
-65% -$87.8K ﹤0.01% 5842
2022
Q3 		$177K Sell
89,838
-52,977
-37% -$138K ﹤0.01% 5728
2022
Q2 		$340K Buy
+142,815
New +$380K ﹤0.01% 5262
2022
Q1 		– Sell
-10,253
Closed -$112K – 7372
2021
Q4 		$112K Buy
+10,253
New +$117K ﹤0.01% 6209

Other funds holding PYXS

P
Pfizer New York $239M AUM 232.47% 1-Year Est. Return
LCM
Laurion Capital Management New York $2.29B AUM 75.73% 1-Year Est. Return
GGI
GordonMD Global Investments Beverely Hills, California $144M AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
HP
HealthInvest Partners Stockholm, Sweden $310M AUM 37.86% 1-Year Est. Return
PAI
Palo Alto Investors Palo Alto, California $654M AUM 77.8% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Millennium Management's PYXS Position: Q1 2026 in Review

Millennium Management reduced its Pyxis Oncology (PYXS) stake by 46% in Q1 2026, selling an estimated $521K and leaving 397,625 shares worth $581K. The position accounts for ﹤0.01% of the portfolio, ranked #4685.

Millennium Management first reported a position in PYXS in Q4 2021 and has held it in 15 quarters since. The position peaked at $7M in Q3 2024. 78 funds tracked by Wall St. Rank hold PYXS as of Q1 2026.

  • Millennium Management held 397,625 shares of Pyxis Oncology worth $581K as of Q1 2026.
  • Millennium Management sold 345,482 Pyxis Oncology shares in Q1 2026, an estimated $521K.
  • Pyxis Oncology made up ﹤0.01% of Millennium Management's portfolio in Q1 2026, its #4685 holding.
  • Millennium Management first reported a position in Pyxis Oncology in Q4 2021 and has held it in 15 quarters since.
  • Millennium Management's Pyxis Oncology position peaked at $7M in Q3 2024.
  • 78 funds tracked by Wall St. Rank held Pyxis Oncology as of Q1 2026.

Based on Millennium Management's 13F filing for Q1 2026, filed 15 May 2026.