John Overdeck Two Sigma Investments
John Overdeck is a co-founder of Two Sigma Investments, one of the world’s leading quantitative and technology-driven investment firms. Two Sigma applies data science, machine learning, and large-scale computing to markets across asset classes. Overdeck’s firm is a central reference point in discussions of modern systematic investing.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Intuit
INTU
|
+$753M |
| 2 |
Boston Scientific
BSX
|
+$540M |
| 3 |
Dow Inc
DOW
|
+$485M |
| 4 |
Wells Fargo
WFC
|
+$457M |
| 5 |
Goldman Sachs
GS
|
+$378M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Micron Technology
MU
|
+$1.32B |
| 2 |
NVIDIA
NVDA
|
+$1.02B |
| 3 |
Alphabet (Google) Class A
GOOGL
|
+$787M |
| 4 |
SNDK
Sandisk
SNDK
|
+$744M |
| 5 |
Dell
DELL
|
+$688M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 19.71% |
| 2 | Financials | 15.22% |
| 3 | Healthcare | 11.94% |
| 4 | Industrials | 11.55% |
| 5 | Consumer Discretionary | 9.6% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
4776
Duos Technologies
DUOT
$324M
| $130K | ﹤0.01% |
+10,836
| New | +$109K |
|
|
ARX
4777
Accelerant Holdings
ARX
$4.25B
| $130K | ﹤0.01% |
+11,079
| New | +$156K |
|
4778
Eledon Pharmaceuticals
ELDN
$280M
| $130K | ﹤0.01% |
+32,945
| New | +$120K |
|
4779
The Honest Company
HNST
$542M
| $129K | ﹤0.01% |
35,315
+615
| +2% | +$2.07K |
|
|
KC
4780
Kingsoft Cloud Holdings
KC
$3.33B
| $129K | ﹤0.01% |
+14,227
| New | +$197K |
|
4781
Delcath Systems
DCTH
$595M
| $127K | ﹤0.01% |
+10,054
| New | +$111K |
|
4782
Upland Software
UPLD
$14.4M
| $125K | ﹤0.01% |
26,790
-14,421
| -35% | -$99.8K |
|
4783
Copel
ELPC
$8.17B
| $124K | ﹤0.01% |
+10,673
| New | +$130K |
|
|
TEAD
4784
Teads Holding Co
TEAD
$65.3M
| $124K | ﹤0.01% |
161,058
-50,381
| -24% | -$49.5K |
|
4785
CALL
Aurora
AUR
$12.5B
| $123K | ﹤0.01% |
+18,000
| New | +$110K |
|
|
LONA
4786
LeonaBio Inc
LONA
$72.4M
| $122K | ﹤0.01% |
13,276
| – | – |
|
4787
Vivid Seats
SEAT
$77.5M
| $119K | ﹤0.01% |
+18,299
| New | +$140K |
|
4788
PepGen
PEPG
$217M
| $119K | ﹤0.01% |
66,268
-115,437
| -64% | -$188K |
|
4789
Sabesp
SBS
$16.2B
| $118K | ﹤0.01% |
+20,495
| New | +$124K |
|
|
TLX
4790
Telix Pharmaceuticals
TLX
$3.84B
| $118K | ﹤0.01% |
+10,233
| New | +$104K |
|
|
IMA
4791
ImageneBio Inc
IMA
$62.5M
| $117K | ﹤0.01% |
+19,900
| New | +$112K |
|
4792
Blend Labs
BLND
$360M
| $116K | ﹤0.01% |
68,008
-22,835
| -25% | -$36.4K |
|
4793
Blink Charging
BLNK
$86.2M
| $116K | ﹤0.01% |
181,486
-45,685
| -20% | -$33.1K |
|
4794
Edesa Biotech
EDSA
$42.7M
| $114K | ﹤0.01% |
+14,032
| New | +$127K |
|
4795
Heron Therapeutics
HRTX
$60.4M
| $114K | ﹤0.01% |
266,314
-51,086
| -16% | -$41K |
|
4796
Pulmonx
LUNG
$97.1M
| $113K | ﹤0.01% |
86,575
+17,963
| +26% | +$24.7K |
|
4797
CVD Equipment Corp
CVV
$52.9M
| $112K | ﹤0.01% |
+15,053
| New | +$91.2K |
|
4798
Motorsport Games
MSGM
$18.2M
| $112K | ﹤0.01% |
27,911
-6,950
| -20% | -$29.4K |
|
4799
NRX Pharmaceuticals
NRXP
$154M
| $108K | ﹤0.01% |
+26,429
| New | +$87.3K |
|
4800
Prairie Operating Co
PROP
$59.6M
| $107K | ﹤0.01% |
148,895
+54,176
| +57% | +$58.4K |
|
Similar funds
John Overdeck's Q2 2026 Portfolio in Review
As of Q2 2026, John Overdeck held 5,589 positions worth $138B, up 11% from $124B the previous quarter. Its ten largest holdings account for 8.3% of the portfolio.
John Overdeck withdrew a net $4.38B in Q2 2026, closing 572 positions and reducing 1,756 holdings. Its most notable exit was State Street Technology Select Sector SPDR ETF, an estimated $172M position sold in full.
By sector, the portfolio is most concentrated in Technology at 20% of assets, up from 19% a quarter earlier, followed by Financials and Healthcare.
Against the trend, John Overdeck opened a new position in Intuit worth $564M.
- John Overdeck's largest Q2 2026 buy was Intuit: 2,161,507 shares worth $564M.
- John Overdeck added most to Boston Scientific in Q2 2026, an estimated $540M increase.
- John Overdeck's biggest Q2 2026 reduction was Micron Technology, cutting an estimated $1.32B.
- John Overdeck fully exited State Street Technology Select Sector SPDR ETF in Q2 2026, selling an estimated $172M.
- John Overdeck's ten largest holdings make up 8.3% of its $138B portfolio in Q2 2026.
- John Overdeck opened 1,050 new positions and closed 572 in Q2 2026.
- John Overdeck's portfolio value rose 11% quarter-over-quarter to $138B.
Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.