John Overdeck’s Vertex Pharmaceuticals VRTX Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q2
$298K Sell
600
-400
-40% -$177K ﹤0.01% 4532
2026
Q1
$447K Buy
+1,000
New +$466K ﹤0.01% 3805
2017
Q2
Sell
-17,200
Closed -$1.88M 3311
2017
Q1
$1.88M Buy
+17,200
New +$1.51M 0.01% 1497
2016
Q3
Sell
-8,000
Closed -$688K 3409
2016
Q2
$688K Buy
+8,000
New +$691K ﹤0.01% 2021

Other funds holding VRTX

John Overdeck's VRTX Position: Q2 2026 in Review

John Overdeck reduced its Vertex Pharmaceuticals (VRTX) stake by 25% in Q2 2026, selling an estimated $41.3M and leaving 285,000 shares worth $142M. The position accounts for 0.1% of the portfolio, ranked #219.

John Overdeck first reported a position in VRTX in Q2 2015 and has held it in 35 quarters since. The position peaked at $174M in Q3 2021. 1,747 funds tracked by Wall St. Rank hold VRTX as of Q2 2026.

  • John Overdeck held 285,000 shares of Vertex Pharmaceuticals worth $142M as of Q2 2026.
  • John Overdeck sold 93,146 Vertex Pharmaceuticals shares in Q2 2026, an estimated $41.3M.
  • Vertex Pharmaceuticals made up 0.1% of John Overdeck's portfolio in Q2 2026, its #219 holding.
  • John Overdeck first reported a position in Vertex Pharmaceuticals in Q2 2015 and has held it in 35 quarters since.
  • John Overdeck's Vertex Pharmaceuticals position peaked at $174M in Q3 2021.
  • 1,747 funds tracked by Wall St. Rank held Vertex Pharmaceuticals as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.