Jim Simons
PYXS icon

Jim Simons’s Pyxis Oncology PYXS Stock Holding History

Jim Simons’s Portfolio PYXS Stock Details PYXS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$2.32M Sell
772,232
-116,448
-13% -$223K ﹤0.01% 1874
2026
Q1 		$1.3M Buy
888,680
+160,300
+22% +$242K ﹤0.01% 2132
2025
Q4 		$838K Buy
728,380
+152,044
+26% +$536K ﹤0.01% 2369
2025
Q3 		$1.28M Buy
576,336
+158,514
+38% +$228K ﹤0.01% 2356
2025
Q2 		$460K Sell
417,822
-164,314
-28% -$185K ﹤0.01% 2876
2025
Q1 		$570K Buy
582,136
+288,782
+98% +$385K ﹤0.01% 2689
2024
Q4 		$458K Buy
293,354
+133,018
+83% +$384K ﹤0.01% 2883
2024
Q3 		$588K Buy
160,336
+63,400
+65% +$222K ﹤0.01% 2710
2024
Q2 		$321K Sell
96,936
-51,064
-35% -$215K ﹤0.01% 2884
2024
Q1 		$630K Sell
148,000
-216,150
-59% -$909K ﹤0.01% 2770
2023
Q4 		$655K Buy
364,150
+147,899
+68% +$253K ﹤0.01% 2650
2023
Q3 		$430K Sell
216,251
-36,978
-15% -$85.7K ﹤0.01% 2780
2023
Q2 		$648K Buy
253,229
+159,029
+169% +$504K ﹤0.01% 2735
2023
Q1 		$378K Buy
94,200
+10,600
+13% +$21.2K ﹤0.01% 3011
2022
Q4 		$112K Sell
83,600
-45,202
-35% -$67.8K ﹤0.01% 3579
2022
Q3 		$254K Buy
128,802
+53,431
+71% +$140K ﹤0.01% 3276
2022
Q2 		$179K Buy
+75,371
New +$201K ﹤0.01% 3690

Other funds holding PYXS

P
Pfizer New York $170M AUM 191.09% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
HP
HealthInvest Partners Stockholm, Sweden $372M AUM 59.89% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $127B AUM 46.06% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
VFT
Vanguard Fiduciary Trust Malvern, Pennsylvania $454B AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return
Bank of New York Mellon
Bank of New York Mellon New York $609B AUM 40.19% 1-Year Est. Return

Jim Simons's PYXS Position: Q2 2026 in Review

Jim Simons reduced its Pyxis Oncology (PYXS) stake by 13% in Q2 2026, selling an estimated $223K and leaving 772,232 shares worth $2.32M. The position accounts for ﹤0.01% of the portfolio, ranked #1874.

Jim Simons first reported a position in PYXS in Q2 2022 and has held it in 17 quarters since. 48 funds tracked by Wall St. Rank hold PYXS as of Q2 2026.

  • Jim Simons held 772,232 shares of Pyxis Oncology worth $2.32M as of Q2 2026.
  • Jim Simons sold 116,448 Pyxis Oncology shares in Q2 2026, an estimated $223K.
  • Pyxis Oncology made up ﹤0.01% of Jim Simons's portfolio in Q2 2026, its #1874 holding.
  • Jim Simons first reported a position in Pyxis Oncology in Q2 2022 and has held it in 17 quarters since.
  • 48 funds tracked by Wall St. Rank held Pyxis Oncology as of Q2 2026.

Based on Renaissance Technologies's 13F filing for Q2 2026, filed 13 Aug 2026.