Jane Street
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Jane Street’s Prothena Corp PRTA Stock Holding History

Jane Street’s Portfolio PRTA Stock Details PRTA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$957K Sell
98,500
-36,500
-27% -$335K ﹤0.01% 6600
2025
Q4 		$1.29M Buy
135,000
+54,500
+68% +$555K ﹤0.01% 5623
2025
Q3 		$786K Buy
80,500
+24,300
+43% +$187K ﹤0.01% 6846
2025
Q2 		$341K Buy
56,200
+42,100
+299% +$316K ﹤0.01% 7633
2025
Q1 		$174K Sell
14,100
-14,600
-51% -$206K ﹤0.01% 8542
2024
Q4 		$397K Buy
28,700
+17,200
+150% +$271K ﹤0.01% 7243
2024
Q3 		$192K Buy
11,500
+500
+5% +$10.8K ﹤0.01% 8670
2024
Q2 		$227K Sell
11,000
-31,800
-74% -$688K ﹤0.01% 8211
2024
Q1 		$1.06M Sell
42,800
-21,900
-34% -$652K ﹤0.01% 5313
2023
Q4 		$2.35M Buy
64,700
+57,800
+838% +$2.22M ﹤0.01% 4043
2023
Q3 		$333K Sell
6,900
-29,400
-81% -$1.75M ﹤0.01% 6913
2023
Q2 		$2.48M Buy
36,300
+22,900
+171% +$1.48M ﹤0.01% 3833
2023
Q1 		$649K Sell
13,400
-19,500
-59% -$1.03M ﹤0.01% 5861
2022
Q4 		$1.98M Sell
32,900
-57,800
-64% -$3.38M ﹤0.01% 3883
2022
Q3 		$5.5M Buy
90,700
+76,900
+557% +$2.43M ﹤0.01% 2457
2022
Q2 		$375K Sell
13,800
-57,100
-81% -$1.67M ﹤0.01% 7233
2022
Q1 		$2.59M Buy
70,900
+41,400
+140% +$1.49M ﹤0.01% 4252
2021
Q4 		$1.46M Sell
29,500
-78,100
-73% -$4.33M ﹤0.01% 5156
2021
Q3 		$7.66M Buy
107,600
+16,600
+18% +$1.03M ﹤0.01% 2153
2021
Q2 		$4.68M Buy
91,000
+53,600
+143% +$1.67M ﹤0.01% 2756
2021
Q1 		$939K Buy
+37,400
New +$704K ﹤0.01% 5574
2018
Q2 		– Sell
-7,600
Closed -$279K – 5476
2018
Q1 		$279K Buy
+7,600
New +$276K ﹤0.01% 4105
2017
Q3 		– Sell
-5,400
Closed -$292K – 4929
2017
Q2 		$292K Buy
+5,400
New +$288K ﹤0.01% 3622

Other funds holding PRTA

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
PAI
Palo Alto Investors Palo Alto, California $654M AUM 77.8% 1-Year Est. Return

Jane Street's PRTA Position: Q1 2026 in Review

Jane Street reduced its Prothena Corp (PRTA) stake by 75% in Q1 2026, selling an estimated $2.94M and leaving 107,926 shares worth $1.05M. The position accounts for ﹤0.01% of the portfolio, ranked #6388.

Jane Street first reported a position in PRTA in Q4 2013 and has held it in 25 quarters since. The position peaked at $6.73M in Q4 2023. 185 funds tracked by Wall St. Rank hold PRTA as of Q1 2026.

  • Jane Street held 107,926 shares of Prothena Corp worth $1.05M as of Q1 2026.
  • Jane Street sold 320,725 Prothena Corp shares in Q1 2026, an estimated $2.94M.
  • Prothena Corp made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #6388 holding.
  • Jane Street first reported a position in Prothena Corp in Q4 2013 and has held it in 25 quarters since.
  • Jane Street's Prothena Corp position peaked at $6.73M in Q4 2023.
  • 185 funds tracked by Wall St. Rank held Prothena Corp as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.