Jane Street
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Jane Street’s Prothena Corp PRTA Stock Holding History

Jane Street’s Portfolio PRTA Stock Details PRTA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$428K Sell
44,000
-92,100
-68% -$844K ﹤0.01% 8414
2025
Q4 		$1.3M Sell
136,100
-42,800
-24% -$436K ﹤0.01% 5605
2025
Q3 		$1.75M Buy
178,900
+35,900
+25% +$276K ﹤0.01% 5191
2025
Q2 		$868K Buy
+143,000
New +$1.07M ﹤0.01% 5880
2024
Q2 		– Sell
-8,100
Closed -$201K – 10012
2024
Q1 		$201K Sell
8,100
-138,700
-94% -$4.13M ﹤0.01% 8181
2023
Q4 		$5.33M Buy
146,800
+140,200
+2,124% +$5.4M ﹤0.01% 2759
2023
Q3 		$318K Sell
6,600
-20,000
-75% -$1.19M ﹤0.01% 6977
2023
Q2 		$1.82M Buy
26,600
+20,700
+351% +$1.34M ﹤0.01% 4309
2023
Q1 		$286K Sell
5,900
-9,700
-62% -$512K ﹤0.01% 7278
2022
Q4 		$940K Sell
15,600
-8,700
-36% -$509K ﹤0.01% 5078
2022
Q3 		$1.47M Buy
24,300
+10,700
+79% +$338K ﹤0.01% 4719
2022
Q2 		$369K Sell
13,600
-600
-4% -$17.6K ﹤0.01% 7257
2022
Q1 		$519K Buy
14,200
+7,800
+122% +$281K ﹤0.01% 7409
2021
Q4 		$316K Sell
6,400
-36,100
-85% -$2M ﹤0.01% 8070
2021
Q3 		$3.03M Buy
42,500
+9,000
+27% +$559K ﹤0.01% 3632
2021
Q2 		$1.72M Buy
+33,500
New +$1.05M ﹤0.01% 4632
2018
Q2 		– Sell
-8,300
Closed -$305K – 5477
2018
Q1 		$305K Buy
+8,300
New +$302K ﹤0.01% 4000

Other funds holding PRTA

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
PAI
Palo Alto Investors Palo Alto, California $654M AUM 77.8% 1-Year Est. Return

Jane Street's PRTA Position: Q1 2026 in Review

Jane Street reduced its Prothena Corp (PRTA) stake by 75% in Q1 2026, selling an estimated $2.94M and leaving 107,926 shares worth $1.05M. The position accounts for ﹤0.01% of the portfolio, ranked #6388.

Jane Street first reported a position in PRTA in Q4 2013 and has held it in 25 quarters since. The position peaked at $6.73M in Q4 2023. 185 funds tracked by Wall St. Rank hold PRTA as of Q1 2026.

  • Jane Street held 107,926 shares of Prothena Corp worth $1.05M as of Q1 2026.
  • Jane Street sold 320,725 Prothena Corp shares in Q1 2026, an estimated $2.94M.
  • Prothena Corp made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #6388 holding.
  • Jane Street first reported a position in Prothena Corp in Q4 2013 and has held it in 25 quarters since.
  • Jane Street's Prothena Corp position peaked at $6.73M in Q4 2023.
  • 185 funds tracked by Wall St. Rank held Prothena Corp as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.