Jane Street’s OptimizeRx OPRX Stock Holding History

Jane Street’s Portfolio OPRX Stock Details OPRX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q3	–	Sell	-11,900	Closed	-$161K	–	11494
2025 Q2	$161K	Sell	11,900 -16,300	-58%	-$178K	﹤0.01%	8702
2025 Q1	$244K	Buy	+28,200	New	+$172K	﹤0.01%	8148
2022 Q2	–	Sell	-17,000	Closed	-$641K	–	10521
2022 Q1	$641K	Sell	17,000 -5,500	-24%	-$243K	﹤0.01%	7012
2021 Q4	$1.4M	Sell	22,500 -12,000	-35%	-$909K	﹤0.01%	5236
2021 Q3	$2.95M	Buy	34,500 +19,600	+132%	+$1.23M	﹤0.01%	3694
2021 Q2	$922K	Sell	14,900 -32,800	-69%	-$1.67M	﹤0.01%	6005
2021 Q1	$2.33M	Buy	+47,700	New	+$2.3M	﹤0.01%	3733

Other funds holding OPRX

WCA

Whetstone Capital Advisors Shawnee Mission, Kansas $380M AUM 20.01% 1-Year Est. Return

Royce & Associates New York $12.4B AUM 64.17% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

KCM

Kennedy Capital Management St Louis, Missouri $5.65B AUM 61.31% 1-Year Est. Return

RHJA

Rice Hall James & Associates San Diego, California $2.05B AUM 43.16% 1-Year Est. Return

William Blair & Company Chicago, Illinois $38.4B AUM 25.71% 1-Year Est. Return

AQR Capital Management Greenwich, Connecticut $287B AUM 42.33% 1-Year Est. Return

Dimensional Fund Advisors Austin, Texas $552B AUM 44.19% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

PHP

Parkman Healthcare Partners Stamford, Connecticut $977M AUM 110.37% 1-Year Est. Return

Jane Street's OPRX Position: Q2 2026 in Review

Jane Street opened a new position in OptimizeRx (OPRX) in Q2 2026: 122,086 shares worth $698K. The stake represents ﹤0.01% of the portfolio and ranks #7298 among its holdings. This is a return to the name: Jane Street previously reported a position in OPRX as recently as Q4 2025.

Jane Street first reported a position in OPRX in Q1 2021 and has held it in 12 quarters since. The position peaked at $1.85M in Q1 2023. 113 funds tracked by Wall St. Rank hold OPRX as of Q2 2026.

Jane Street held 122,086 shares of OptimizeRx worth $698K as of Q2 2026.
OptimizeRx was a new Jane Street position in Q2 2026.
OptimizeRx made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #7298 holding.
Jane Street first reported a position in OptimizeRx in Q1 2021 and has held it in 12 quarters since.
Jane Street's OptimizeRx position peaked at $1.85M in Q1 2023.
113 funds tracked by Wall St. Rank held OptimizeRx as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.