Jane Street
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Jane Street’s OptimizeRx OPRX Stock Holding History

Jane Street’s Portfolio OPRX Stock Details OPRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$171K Sell
27,200
-26,800
-50% -$249K ﹤0.01% 10286
2025
Q4 		$662K Buy
54,000
+40,300
+294% +$658K ﹤0.01% 7088
2025
Q3 		$281K Sell
13,700
-39,700
-74% -$630K ﹤0.01% 9036
2025
Q2 		$721K Buy
53,400
+30,000
+128% +$328K ﹤0.01% 6245
2025
Q1 		$203K Buy
+23,400
New +$143K ﹤0.01% 8429
2024
Q3 		– Sell
-10,000
Closed -$100K – 10170
2024
Q2 		$100K Buy
+10,000
New +$110K ﹤0.01% 8725
2023
Q1 		– Sell
-13,500
Closed -$227K – 9680
2022
Q4 		$227K Buy
13,500
+3,100
+30% +$53.6K ﹤0.01% 7472
2022
Q3 		$154K Sell
10,400
-19,200
-65% -$380K ﹤0.01% 8383
2022
Q2 		$811K Sell
29,600
-79,300
-73% -$2.35M ﹤0.01% 5870
2022
Q1 		$4.11M Buy
108,900
+36,700
+51% +$1.62M ﹤0.01% 3370
2021
Q4 		$4.48M Buy
72,200
+13,200
+22% +$1M ﹤0.01% 3032
2021
Q3 		$5.05M Buy
59,000
+3,500
+6% +$220K ﹤0.01% 2714
2021
Q2 		$3.44M Sell
55,500
-15,800
-22% -$804K ﹤0.01% 3327
2021
Q1 		$3.48M Buy
+71,300
New +$3.44M ﹤0.01% 2977

Other funds holding OPRX

WCA
Whetstone Capital Advisors Shawnee Mission, Kansas $288M AUM 44.06% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
RA
Royce & Associates New York $10.1B AUM 42.88% 1-Year Est. Return
PHP
Parkman Healthcare Partners Stamford, Connecticut $970M AUM 79.46% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
KCM
Kennedy Capital Management St Louis, Missouri $4.72B AUM 36.69% 1-Year Est. Return
William Blair & Company
William Blair & Company Chicago, Illinois $34.9B AUM 18.88% 1-Year Est. Return
RHJA
Rice Hall James & Associates San Diego, California $1.8B AUM 36.16% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Jane Street's OPRX Position: Q1 2026 in Review

Jane Street sold out of OptimizeRx (OPRX) in Q1 2026, closing a stake of 87,481 shares — an estimated $812K sold.

Jane Street first reported a position in OPRX in Q1 2021 and held it in 11 quarters. The position peaked at $1.85M in Q1 2023. 128 funds tracked by Wall St. Rank hold OPRX as of Q1 2026.

  • Jane Street reported no remaining OptimizeRx position as of Q1 2026 after selling out during the quarter.
  • Jane Street sold 87,481 OptimizeRx shares in Q1 2026, an estimated $812K.
  • Jane Street first reported a position in OptimizeRx in Q1 2021 and held it in 11 quarters.
  • Jane Street's OptimizeRx position peaked at $1.85M in Q1 2023.
  • 128 funds tracked by Wall St. Rank held OptimizeRx as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.