Jane Street’s OptimizeRx OPRX Stock Holding History

Jane Street’s Portfolio OPRX Stock Details OPRX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$698K	Buy	+122,086	New	+$702K	﹤0.01%	7298
2026 Q1	–	Sell	-87,481	Closed	-$812K	–	12601
2025 Q4	$1.07M	Buy	+87,481	New	+$1.43M	﹤0.01%	5977
2025 Q1	–	Sell	-72,454	Closed	-$443K	–	10284
2024 Q4	$352K	Buy	72,454 +50,808	+235%	+$284K	﹤0.01%	7465
2024 Q3	$167K	Sell	21,646 -12,682	-37%	-$113K	﹤0.01%	8757
2024 Q2	$343K	Buy	34,328 +6,173	+22%	+$67.8K	﹤0.01%	7590
2024 Q1	$342K	Buy	+28,155	New	+$408K	﹤0.01%	7341
2023 Q2	–	Sell	-126,652	Closed	-$1.85M	–	9314
2023 Q1	$1.85M	Buy	+126,652	New	+$2.12M	﹤0.01%	3962
2022 Q2	–	Sell	-15,299	Closed	-$453K	–	10520
2022 Q1	$577K	Buy	15,299 +10,623	+227%	+$470K	﹤0.01%	7195
2021 Q4	$290K	Sell	4,676 -7,503	-62%	-$569K	﹤0.01%	8226
2021 Q3	$1.04M	Buy	12,179 +3,770	+45%	+$237K	﹤0.01%	5824
2021 Q2	$521K	Sell	8,409 -3,383	-29%	-$172K	﹤0.01%	7158
2021 Q1	$575K	Buy	+11,792	New	+$569K	﹤0.01%	6551

Other funds holding OPRX

WCA

Whetstone Capital Advisors Shawnee Mission, Kansas $380M AUM 20.01% 1-Year Est. Return

Royce & Associates New York $12.4B AUM 64.17% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

KCM

Kennedy Capital Management St Louis, Missouri $5.65B AUM 61.31% 1-Year Est. Return

RHJA

Rice Hall James & Associates San Diego, California $2.05B AUM 43.16% 1-Year Est. Return

William Blair & Company Chicago, Illinois $38.4B AUM 25.71% 1-Year Est. Return

AQR Capital Management Greenwich, Connecticut $287B AUM 42.33% 1-Year Est. Return

Dimensional Fund Advisors Austin, Texas $552B AUM 44.19% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

PHP

Parkman Healthcare Partners Stamford, Connecticut $977M AUM 110.37% 1-Year Est. Return

Jane Street's OPRX Position: Q2 2026 in Review

Jane Street opened a new position in OptimizeRx (OPRX) in Q2 2026: 122,086 shares worth $698K. The stake represents ﹤0.01% of the portfolio and ranks #7298 among its holdings. This is a return to the name: Jane Street previously reported a position in OPRX as recently as Q4 2025.

Jane Street first reported a position in OPRX in Q1 2021 and has held it in 12 quarters since. The position peaked at $1.85M in Q1 2023. 113 funds tracked by Wall St. Rank hold OPRX as of Q2 2026.

Jane Street held 122,086 shares of OptimizeRx worth $698K as of Q2 2026.
OptimizeRx was a new Jane Street position in Q2 2026.
OptimizeRx made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #7298 holding.
Jane Street first reported a position in OptimizeRx in Q1 2021 and has held it in 12 quarters since.
Jane Street's OptimizeRx position peaked at $1.85M in Q1 2023.
113 funds tracked by Wall St. Rank held OptimizeRx as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.