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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
D icon
201
Dominion Energy
D
$59.8B
$10.7K 0.01%
183
– –
CAH icon
202
Cardinal Health
CAH
$54.5B
$10.7K 0.01%
52
– –
DLR icon
203
Digital Realty Trust
DLR
$72.9B
$10.7K 0.01%
69
+1
+1% +$164
MPC icon
204
Marathon Petroleum
MPC
$97.8B
$10.6K 0.01%
65
-1
-2% -$187
CMG icon
205
Chipotle Mexican Grill
CMG
$41.3B
$10.5K 0.01%
284
-4
-1% -$145
ROP icon
206
Roper Technologies
ROP
$39.1B
$10.2K 0.01%
23
– –
AZO icon
207
AutoZone
AZO
$49.7B
$10.2K 0.01%
3
– –
CBRE icon
208
CBRE Group
CBRE
$42.7B
$10.1K 0.01%
63
– –
AME icon
209
Ametek
AME
$59.3B
$10.1K 0.01%
49
– –
EA
210
DELISTED
Electronic Arts
EA
$10K 0.01%
49
– –
AIG icon
211
American International
AIG
$39.8B
$10K 0.01%
117
-2
-2% -$160
OKE icon
212
Oneok
OKE
$58.3B
$9.92K 0.01%
135
– –
FAST icon
213
Fastenal
FAST
$59.9B
$9.91K 0.01%
247
+1
+0.4% +$42
WDAY icon
214
Workday
WDAY
$43.3B
$9.88K 0.01%
46
– –
AMP icon
215
Ameriprise Financial
AMP
$49.9B
$9.81K 0.01%
20
– –
CTVA icon
216
Corteva
CTVA
$50.4B
$9.79K 0.01%
146
– –
BKR icon
217
Baker Hughes
BKR
$63.8B
$9.7K 0.01%
213
+1
+0.5% +$47
DAL icon
218
Delta Air Lines
DAL
$59.1B
$9.65K 0.01%
139
– –
TGT icon
219
Target
TGT
$69.9B
$9.58K 0.01%
98
– –
MET icon
220
MetLife
MET
$61.4B
$9.47K 0.01%
120
– –
TTWO icon
221
Take-Two Interactive
TTWO
$45.4B
$9.47K 0.01%
37
– –
EXC icon
222
Exelon
EXC
$46.6B
$9.46K 0.01%
217
– –
NDAQ icon
223
Nasdaq
NDAQ
$53.5B
$9.42K 0.01%
97
– –
DDOG icon
224
Datadog
DDOG
$86.5B
$9.38K 0.01%
69
– –
XEL icon
225
Xcel Energy
XEL
$49.1B
$9.38K 0.01%
127
– –
7 8
9
10 11

Similar funds

VM
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SSC
Spruce Street Capital New York $416M AUM
ACM
Alight Capital Management New York $417M AUM 98.18% 1-Year Est. Return
MCM
Millstreet Capital Management Boston, Massachusetts $418M AUM 80.77% 1-Year Est. Return
MIA
Milestone Investment Advisors Middleton, Wisconsin $414M AUM 12.76% 1-Year Est. Return
SP
Sequent Planning Omaha, Nebraska $414M AUM 14.63% 1-Year Est. Return
SWC
Square Wave Capital Brooklyn, New York $413M AUM 15.36% 1-Year Est. Return
VIS
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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.