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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
FAST icon
201
Fastenal
FAST
$53.5B
– –
-247
Closed -$9.91K
FCX icon
202
Freeport-McMoran
FCX
$91.2B
– –
-309
Closed -$15.7K
FDS icon
203
Factset
FDS
$9.35B
– –
-8
Closed -$2.32K
FDX icon
204
FedEx
FDX
$73B
– –
-47
Closed -$13.6K
FE icon
205
FirstEnergy
FE
$28.2B
– –
-111
Closed -$4.97K
FFIV icon
206
F5
FFIV
$22.1B
– –
-12
Closed -$3.06K
FISV
207
Fiserv Inc
FISV
$28.8B
– –
-116
Closed -$7.79K
FICO icon
208
Fair Isaac
FICO
$26.4B
– –
-5
Closed -$8.45K
FIS icon
209
Fidelity National Information Services
FIS
$23.8B
– –
-112
Closed -$7.44K
FITB
210
Fifth Third Bancorp
FITB
$51.3B
– –
-143
Closed -$6.69K
FIX icon
211
Comfort Systems
FIX
$59.8B
– –
-7
Closed -$6.53K
FOX icon
212
Fox Class B
FOX
$22B
– –
-31
Closed -$2.01K
FOXA icon
213
Fox Class A
FOXA
$24.7B
– –
-45
Closed -$3.29K
FRT icon
214
Federal Realty Investment Trust
FRT
$10.7B
– –
-16
Closed -$1.61K
FSLR icon
215
First Solar
FSLR
$22.1B
– –
-23
Closed -$6.01K
FTNT icon
216
Fortinet
FTNT
$113B
– –
-137
Closed -$10.9K
FTV icon
217
Fortive
FTV
$17.7B
– –
-69
Closed -$3.81K
GD icon
218
General Dynamics
GD
$103B
– –
-54
Closed -$18.2K
GDDY icon
219
GoDaddy
GDDY
$13.2B
– –
-30
Closed -$3.72K
GE icon
220
GE Aerospace
GE
$368B
– –
-228
Closed -$70.2K
GEHC icon
221
GE HealthCare
GEHC
$31.6B
– –
-98
Closed -$8.04K
GEN icon
222
Gen Digital
GEN
$16.3B
– –
-121
Closed -$3.29K
GILD icon
223
Gilead Sciences
GILD
$163B
– –
-268
Closed -$32.9K
GIS icon
224
General Mills
GIS
$19.4B
– –
-115
Closed -$5.35K
GL icon
225
Globe Life
GL
$14.2B
– –
-18
Closed -$2.52K
7 8
9
10 11

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.