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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
EFX icon
176
Equifax
EFX
$20.7B
– –
-26
Closed -$5.64K
EG icon
177
Everest Group
EG
$14.9B
– –
-9
Closed -$3.05K
EIX icon
178
Edison International
EIX
$30.3B
– –
-83
Closed -$4.98K
EL icon
179
Estee Lauder
EL
$30.7B
– –
-52
Closed -$5.45K
ELV icon
180
Elevance Health
ELV
$81.6B
– –
-48
Closed -$16.8K
EME icon
181
Emcor
EME
$35.7B
– –
-9
Closed -$5.51K
EMR icon
182
Emerson Electric
EMR
$83.3B
– –
-121
Closed -$16.1K
EOG icon
183
EOG Resources
EOG
$77.5B
– –
-117
Closed -$12.3K
EPAM icon
184
EPAM Systems
EPAM
$5.42B
– –
-12
Closed -$2.46K
EQIX icon
185
Equinix
EQIX
$103B
– –
-21
Closed -$16.1K
EQR icon
186
Equity Residential
EQR
$25.2B
– –
-74
Closed -$4.67K
EQT icon
187
EQT Corp
EQT
$33B
– –
-134
Closed -$7.18K
ERIE icon
188
Erie Indemnity
ERIE
$12.2B
– –
-5
Closed -$1.43K
ES icon
189
Eversource Energy
ES
$27.8B
– –
-80
Closed -$5.39K
ESS icon
190
Essex Property Trust
ESS
$18.1B
– –
-13
Closed -$3.4K
ETN icon
191
Eaton
ETN
$150B
– –
-84
Closed -$26.8K
ETR icon
192
Entergy
ETR
$50.4B
– –
-96
Closed -$8.87K
EVRG icon
193
Evergy
EVRG
$19.2B
– –
-49
Closed -$3.55K
EW icon
194
Edwards Lifesciences
EW
$50B
– –
-126
Closed -$10.7K
EXC icon
195
Exelon
EXC
$46.6B
– –
-217
Closed -$9.46K
EXPD icon
196
Expeditors International
EXPD
$21.8B
– –
-29
Closed -$4.32K
EXPE icon
197
Expedia Group
EXPE
$35.2B
– –
-26
Closed -$7.37K
EXR icon
198
Extra Space Storage
EXR
$31.3B
– –
-45
Closed -$5.86K
F icon
199
Ford
F
$59.3B
– –
-843
Closed -$11.1K
FANG icon
200
Diamondback Energy
FANG
$56.2B
– –
-40
Closed -$6.01K
6 7
8
9 10

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.