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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ABNB icon
176
Airbnb
ABNB
$108B
$12.5K 0.01%
92
-1
-1% -$125
PCAR icon
177
PACCAR
PCAR
$69B
$12.4K 0.01%
113
– –
SRE icon
178
Sempra
SRE
$56.2B
$12.4K 0.01%
140
– –
SLB icon
179
SLB Ltd
SLB
$78.1B
$12.4K 0.01%
322
+2
+0.6% +$73
EOG icon
180
EOG Resources
EOG
$75.1B
$12.3K 0.01%
117
-1
-0.8% -$107
BDX icon
181
Becton Dickinson
BDX
$50B
$12K 0.01%
62
– –
ZTS icon
182
Zoetis
ZTS
$30.4B
$12K 0.01%
95
-1
-1% -$130
ALL icon
183
Allstate
ALL
$64.7B
$11.9K 0.01%
57
– –
APD icon
184
Air Products & Chemicals
APD
$67.7B
$11.9K 0.01%
48
– –
LHX icon
185
L3Harris
LHX
$54.1B
$11.7K 0.01%
40
– –
PYPL icon
186
PayPal
PYPL
$50.6B
$11.7K 0.01%
201
-5
-2% -$325
MNST icon
187
Monster Beverage
MNST
$90.1B
$11.7K 0.01%
306
– –
NXPI icon
188
NXP Semiconductors
NXPI
$58.9B
$11.7K 0.01%
54
– –
KMI icon
189
Kinder Morgan
KMI
$70.7B
$11.6K 0.01%
421
+2
+0.5% +$54
IDXX icon
190
Idexx Laboratories
IDXX
$45B
$11.5K 0.01%
17
– –
URI icon
191
United Rentals
URI
$70.3B
$11.3K 0.01%
14
– –
AFL icon
192
Aflac
AFL
$60.5B
$11.2K 0.01%
102
-2
-2% -$220
PSX icon
193
Phillips 66
PSX
$90B
$11.2K 0.01%
87
– –
O icon
194
Realty Income
O
$59.2B
$11.2K 0.01%
198
+2
+1% +$116
VST icon
195
Vistra
VST
$49.2B
$11.1K 0.01%
69
– –
F icon
196
Ford
F
$55.1B
$11.1K 0.01%
843
+3
+0.4% +$39
FTNT icon
197
Fortinet
FTNT
$118B
$10.9K 0.01%
137
-2
-1% -$166
COIN icon
198
Coinbase
COIN
$39.3B
$10.9K 0.01%
48
– –
VLO icon
199
Valero Energy
VLO
$95.1B
$10.7K 0.01%
66
-1
-1% -$169
EW icon
200
Edwards Lifesciences
EW
$53.6B
$10.7K 0.01%
126
-1
-0.8% -$82
6 7
8
9 10

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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.