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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
151
Fortinet
FTNT
$118B
| $14.5K | 0.01% |
+137
| New | +$13.8K |
|
152
EOG Resources
EOG
$75.1B
| $14.5K | 0.01% |
+121
| New | +$13.8K |
|
153
Newmont
NEM
$124B
| $14.3K | 0.01% |
+246
| New | +$13.1K |
|
154
Autodesk
ADSK
$52.7B
| $14.2K | 0.01% |
+46
| New | +$13.1K |
|
155
Vistra
VST
$49.2B
| $14.1K | 0.01% |
+73
| New | +$10.8K |
|
|
BNY
156
Bank of New York Mellon
BNY
$111B
| $14.1K | 0.01% |
+155
| New | +$13.2K |
|
157
Illinois Tool Works
ITW
$83.3B
| $14.1K | 0.01% |
+57
| New | +$13.8K |
|
158
Apollo Global Management
APO
$81.9B
| $13.6K | 0.01% |
+96
| New | +$12.7K |
|
159
Hilton Worldwide
HLT
$72.6B
| $13.6K | 0.01% |
+51
| New | +$12.1K |
|
160
CSX Corp
CSX
$92.8B
| $13.6K | 0.01% |
+416
| New | +$12.5K |
|
161
Air Products & Chemicals
APD
$67.7B
| $13.5K | 0.01% |
+48
| New | +$13.1K |
|
162
Freeport-McMoran
FCX
$96.9B
| $13.4K | 0.01% |
+310
| New | +$11.8K |
|
163
Marriott International
MAR
$92.5B
| $13.4K | 0.01% |
+49
| New | +$12.3K |
|
164
Travelers Companies
TRV
$77.2B
| $13.1K | 0.01% |
+49
| New | +$12.9K |
|
165
Roper Technologies
ROP
$39.1B
| $13K | 0.01% |
+23
| New | +$13K |
|
166
Carrier Global
CARR
$52B
| $12.7K | 0.01% |
+174
| New | +$11.8K |
|
|
AXON
167
Axon Enterprise
AXON
$48.7B
| $12.4K | ﹤0.01% |
+15
| New | +$10.2K |
|
168
Airbnb
ABNB
$108B
| $12.3K | ﹤0.01% |
+93
| New | +$11.8K |
|
169
Norfolk Southern
NSC
$75.3B
| $12.3K | ﹤0.01% |
+48
| New | +$11.3K |
|
170
Kinder Morgan
KMI
$70.7B
| $12.3K | ﹤0.01% |
+417
| New | +$11.4K |
|
171
Truist Financial
TFC
$64.3B
| $12.2K | ﹤0.01% |
+284
| New | +$11.1K |
|
172
American Electric Power
AEP
$67.9B
| $11.9K | ﹤0.01% |
+115
| New | +$12K |
|
173
Digital Realty Trust
DLR
$72.9B
| $11.9K | ﹤0.01% |
+68
| New | +$11.1K |
|
174
NXP Semiconductors
NXPI
$58.9B
| $11.8K | ﹤0.01% |
+54
| New | +$10.5K |
|
175
Quanta Services
PWR
$102B
| $11.7K | ﹤0.01% |
+31
| New | +$9.95K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.