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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
AMT icon
126
American Tower
AMT
$79.4B
$17.6K 0.01%
100
BNY
127
Bank of New York Mellon
BNY
$111B
$17.5K 0.01%
151
-1
-0.7% -$111
WM icon
128
Waste Management
WM
$90.5B
$17.4K 0.01%
79
REGN icon
129
Regeneron Pharmaceuticals
REGN
$82.2B
$17K 0.01%
22
MCO icon
130
Moody's
MCO
$82.8B
$16.9K 0.01%
33
ELV icon
131
Elevance Health
ELV
$86.6B
$16.8K 0.01%
48
-1
-2% -$338
ORLY icon
132
O'Reilly Automotive
ORLY
$74.5B
$16.7K 0.01%
183
NOC icon
133
Northrop Grumman
NOC
$82B
$16.5K 0.01%
29
GM icon
134
General Motors
GM
$76.1B
$16.3K 0.01%
201
-4
-2% -$282
HCA icon
135
HCA Healthcare
HCA
$89.8B
$16.3K 0.01%
35
-1
-3% -$464
NKE icon
136
Nike
NKE
$60.1B
$16.2K 0.01%
255
AON icon
137
Aon
AON
$74.7B
$16.2K 0.01%
46
SHW icon
138
Sherwin-Williams
SHW
$87.4B
$16.2K 0.01%
50
EQIX icon
139
Equinix
EQIX
$105B
$16.1K 0.01%
21
EMR icon
140
Emerson Electric
EMR
$91.4B
$16.1K 0.01%
121
CI icon
141
Cigna
CI
$73.3B
$16K 0.01%
58
TDG icon
142
TransDigm Group
TDG
$68.3B
$16K 0.01%
12
WMB icon
143
Williams Companies
WMB
$90.1B
$15.8K 0.01%
263
JCI icon
144
Johnson Controls International
JCI
$92.6B
$15.8K 0.01%
132
-9
-6% -$1.03K
UPS icon
145
United Parcel Service
UPS
$88.4B
$15.8K 0.01%
159
+1
+0.6% +$94
FCX icon
146
Freeport-McMoran
FCX
$96.9B
$15.7K 0.01%
309
WBD icon
147
Warner Bros
WBD
$69.3B
$15.3K 0.01%
531
RCL icon
148
Royal Caribbean
RCL
$82.4B
$15.1K 0.01%
54
MDLZ icon
149
Mondelez International
MDLZ
$79.4B
$15K 0.01%
278
MAR icon
150
Marriott International
MAR
$92.5B
$14.9K 0.01%
48
-1
-2% -$286

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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.