We are live on ! Find out more
HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+7.99%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$171M
AUM Growth
-$80.3M
Cap. Flow
-$96.1M
Cap. Flow %
-56.34%
Top 10 Hldgs %
95.55%
Holding
509
New
8
Increased
62
Reduced
141
Closed
9

Top Buys

Rank Stock Value
1
APP icon
Applovin
APP
+$26.7K
2
HOOD icon
Robinhood
HOOD
+$18.1K
3
AMZN icon
Amazon
AMZN
+$10.2K
4
DDOG icon
Datadog
DDOG
+$9.5K
5
XYZ
Block Inc
XYZ
+$8.91K

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$96.2M
2
AAPL icon
Apple
AAPL
+$9.94K
3
HES
Hess
HES
+$8.17K
4
NVDA icon
NVIDIA
NVDA
+$7.84K
5
MSFT icon
Microsoft
MSFT
+$7.14K

Sector Composition

Rank Sector Weight
1 Technology 2.56%
2 Financials 0.95%
3 Consumer Discretionary 0.76%
4 Communication Services 0.75%
5 Healthcare 0.64%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
RCL icon
126
Royal Caribbean
RCL
$82.4B
$17.5K 0.01%
54
+1
+2% +$334
WM icon
127
Waste Management
WM
$90.5B
$17.4K 0.01%
79
+1
+1% +$225
MDLZ icon
128
Mondelez International
MDLZ
$79.4B
$17.4K 0.01%
278
-1
-0.4% -$64
SHW icon
129
Sherwin-Williams
SHW
$87.4B
$17.3K 0.01%
50
– –
PNC icon
130
PNC Financial Services
PNC
$102B
$17.1K 0.01%
85
– –
HWM icon
131
Howmet Aerospace
HWM
$112B
$17.1K 0.01%
87
– –
AJG icon
132
Arthur J. Gallagher & Co
AJG
$65.5B
$17K 0.01%
55
+1
+2% +$301
CI icon
133
Cigna
CI
$73.3B
$16.7K 0.01%
58
-1
-2% -$296
WMB icon
134
Williams Companies
WMB
$90.1B
$16.7K 0.01%
263
– –
BNY
135
Bank of New York Mellon
BNY
$111B
$16.6K 0.01%
152
-3
-2% -$306
MSI icon
136
Motorola Solutions
MSI
$77.7B
$16.5K 0.01%
36
– –
EQIX icon
137
Equinix
EQIX
$105B
$16.4K 0.01%
21
– –
AON icon
138
Aon
AON
$74.7B
$16.4K 0.01%
46
– –
COIN icon
139
Coinbase
COIN
$39.3B
$16.2K 0.01%
48
+3
+7% +$1.02K
USB icon
140
US Bancorp
USB
$101B
$16.2K 0.01%
335
-2
-0.6% -$95
EMR icon
141
Emerson Electric
EMR
$91.4B
$15.9K 0.01%
121
– –
ELV icon
142
Elevance Health
ELV
$86.6B
$15.8K 0.01%
49
-1
-2% -$311
TDG icon
143
TransDigm Group
TDG
$68.3B
$15.8K 0.01%
12
– –
MCO icon
144
Moody's
MCO
$82.8B
$15.7K 0.01%
33
– –
JCI icon
145
Johnson Controls International
JCI
$92.6B
$15.5K 0.01%
141
-1
-0.7% -$107
HCA icon
146
HCA Healthcare
HCA
$89.8B
$15.3K 0.01%
36
-2
-5% -$775
CTAS icon
147
Cintas
CTAS
$81.4B
$15.2K 0.01%
74
– –
FISV
148
Fiserv Inc
FISV
$27.4B
$15.1K 0.01%
117
-5
-4% -$717
ITW icon
149
Illinois Tool Works
ITW
$83.3B
$14.9K 0.01%
57
– –
ECL icon
150
Ecolab
ECL
$78.1B
$14.8K 0.01%
54
– –
4 5
6
7 8

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
ACM
Alight Capital Management New York $417M AUM 98.18% 1-Year Est. Return
MCM
Millstreet Capital Management Boston, Massachusetts $418M AUM 80.77% 1-Year Est. Return
MIA
Milestone Investment Advisors Middleton, Wisconsin $414M AUM 12.76% 1-Year Est. Return
SP
Sequent Planning Omaha, Nebraska $414M AUM 14.63% 1-Year Est. Return
SWC
Square Wave Capital Brooklyn, New York $413M AUM 15.36% 1-Year Est. Return
VIS
Vega Investment Solutions Paris, France $418M AUM

Howard Hughes Medical Institute's Q3 2025 Portfolio in Review

As of Q3 2025, Howard Hughes Medical Institute held 509 positions worth $171M, down 32% from $251M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Howard Hughes Medical Institute withdrew a net $96.1M in Q3 2025, closing 9 positions and reducing 141 holdings. Its most notable exit was Hess, an estimated $8.17K position sold in full.

By sector, the portfolio is most concentrated in Technology at 2.6% of assets, up from 1.6% a quarter earlier, followed by Financials and Consumer Discretionary.

Against the trend, Howard Hughes Medical Institute opened a new position in Applovin worth $41.7K.

  • Howard Hughes Medical Institute's largest Q3 2025 buy was Applovin: 58 shares worth $41.7K.
  • Howard Hughes Medical Institute added most to Amazon in Q3 2025, an estimated $10.2K increase.
  • Howard Hughes Medical Institute's biggest Q3 2025 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $96.2M.
  • Howard Hughes Medical Institute fully exited Hess in Q3 2025, selling an estimated $8.17K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $171M portfolio in Q3 2025.
  • Howard Hughes Medical Institute opened 8 new positions and closed 9 in Q3 2025.
  • Howard Hughes Medical Institute's portfolio value fell 32% quarter-over-quarter to $171M.

Based on Howard Hughes Medical Institute's 13F filing for Q3 2025, filed 14 Nov 2025.