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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
126
Sherwin-Williams
SHW
$87.4B
| $17.2K | 0.01% |
+50
| New | +$17.3K |
|
127
Synopsys
SNPS
$79B
| $16.9K | 0.01% |
+33
| New | +$15.4K |
|
128
O'Reilly Automotive
ORLY
$74.5B
| $16.8K | 0.01% |
+186
| New | +$17K |
|
129
Equinix
EQIX
$105B
| $16.7K | 0.01% |
+21
| New | +$17.8K |
|
130
Royal Caribbean
RCL
$82.4B
| $16.6K | 0.01% |
+53
| New | +$12.6K |
|
131
Moody's
MCO
$82.8B
| $16.6K | 0.01% |
+33
| New | +$15.3K |
|
132
Williams Companies
WMB
$90.1B
| $16.5K | 0.01% |
+263
| New | +$15.5K |
|
133
Cintas
CTAS
$81.4B
| $16.5K | 0.01% |
+74
| New | +$15.9K |
|
134
Aon
AON
$74.7B
| $16.4K | 0.01% |
+46
| New | +$16.7K |
|
135
Chipotle Mexican Grill
CMG
$41.3B
| $16.4K | 0.01% |
+292
| New | +$14.9K |
|
136
Howmet Aerospace
HWM
$112B
| $16.2K | 0.01% |
+87
| New | +$13.4K |
|
137
Emerson Electric
EMR
$91.4B
| $16.1K | 0.01% |
+121
| New | +$13.9K |
|
138
United Parcel Service
UPS
$88.4B
| $15.9K | 0.01% |
+158
| New | +$15.5K |
|
139
Colgate-Palmolive
CL
$73.6B
| $15.9K | 0.01% |
+175
| New | +$16K |
|
140
PNC Financial Services
PNC
$102B
| $15.8K | 0.01% |
+85
| New | +$14.4K |
|
141
PayPal
PYPL
$50.6B
| $15.8K | 0.01% |
+213
| New | +$14.6K |
|
142
Coinbase
COIN
$39.3B
| $15.8K | 0.01% |
+45
| New | +$10.5K |
|
143
General Dynamics
GD
$107B
| $15.8K | 0.01% |
+54
| New | +$14.9K |
|
144
US Bancorp
USB
$101B
| $15.2K | 0.01% |
+337
| New | +$14.2K |
|
145
Motorola Solutions
MSI
$77.7B
| $15.1K | 0.01% |
+36
| New | +$15.1K |
|
146
Johnson Controls International
JCI
$92.6B
| $15K | 0.01% |
+142
| New | +$13.1K |
|
147
Zoetis
ZTS
$30.4B
| $15K | 0.01% |
+96
| New | +$15.2K |
|
148
HCA Healthcare
HCA
$89.8B
| $14.6K | 0.01% |
+38
| New | +$13.7K |
|
149
Ecolab
ECL
$78.1B
| $14.6K | 0.01% |
+54
| New | +$13.7K |
|
150
Northrop Grumman
NOC
$82B
| $14.5K | 0.01% |
+29
| New | +$14.3K |
|
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VIS
Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.