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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
NEM icon
101
Newmont
NEM
$124B
$23.5K 0.01%
235
-1
-0.4% -$90
CMCSA icon
102
Comcast
CMCSA
$90.4B
$23.4K 0.01%
783
-8
-1% -$228
ADP icon
103
Automatic Data Processing
ADP
$107B
$22.4K 0.01%
87
MCK icon
104
McKesson
MCK
$102B
$22.1K 0.01%
27
CVS icon
105
CVS Health
CVS
$121B
$21.7K 0.01%
273
+1
+0.4% +$79
LMT icon
106
Lockheed Martin
LMT
$140B
$21.3K 0.01%
44
-1
-2% -$479
CME icon
107
CME Group
CME
$94.3B
$21K 0.01%
77
TMUS icon
108
T-Mobile US
TMUS
$190B
$20.9K 0.01%
103
SO icon
109
Southern Company
SO
$106B
$20.7K 0.01%
237
+1
+0.4% +$91
SBUX icon
110
Starbucks
SBUX
$124B
$20.6K 0.01%
245
ICE icon
111
Intercontinental Exchange
ICE
$85B
$19.9K 0.01%
123
MRSH
112
Marsh
MRSH
$90.1B
$19.7K 0.01%
106
DUK icon
113
Duke Energy
DUK
$96.3B
$19.6K 0.01%
167
HOOD icon
114
Robinhood
HOOD
$85.3B
$19.1K 0.01%
169
+3
+2% +$390
KKR icon
115
KKR & Co
KKR
$99.5B
$18.7K 0.01%
147
TT icon
116
Trane Technologies
TT
$105B
$18.7K 0.01%
48
CDNS icon
117
Cadence Design Systems
CDNS
$89B
$18.4K 0.01%
59
MMM icon
118
3M
MMM
$94.8B
$18.4K 0.01%
115
SNPS icon
119
Synopsys
SNPS
$79B
$18.3K 0.01%
39
GD icon
120
General Dynamics
GD
$107B
$18.2K 0.01%
54
DASH icon
121
DoorDash
DASH
$92.1B
$18.1K 0.01%
80
+1
+1% +$235
CRH icon
122
CRH
CRH
$65.2B
$18K 0.01%
+144
New +$17.2K
USB icon
123
US Bancorp
USB
$101B
$17.9K 0.01%
335
HWM icon
124
Howmet Aerospace
HWM
$112B
$17.8K 0.01%
87
PNC icon
125
PNC Financial Services
PNC
$102B
$17.7K 0.01%
85

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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.