We are live on ! Find out more
HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+7.99%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$171M
AUM Growth
-$80.3M
Cap. Flow
-$96.1M
Cap. Flow %
-56.34%
Top 10 Hldgs %
95.55%
Holding
509
New
8
Increased
62
Reduced
141
Closed
9

Top Buys

Rank Stock Value
1
APP icon
Applovin
APP
+$26.7K
2
HOOD icon
Robinhood
HOOD
+$18.1K
3
AMZN icon
Amazon
AMZN
+$10.2K
4
DDOG icon
Datadog
DDOG
+$9.5K
5
XYZ
Block Inc
XYZ
+$8.91K

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$96.2M
2
AAPL icon
Apple
AAPL
+$9.94K
3
HES
Hess
HES
+$8.17K
4
NVDA icon
NVIDIA
NVDA
+$7.84K
5
MSFT icon
Microsoft
MSFT
+$7.14K

Sector Composition

Rank Sector Weight
1 Technology 2.56%
2 Financials 0.95%
3 Consumer Discretionary 0.76%
4 Communication Services 0.75%
5 Healthcare 0.64%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LMT icon
101
Lockheed Martin
LMT
$140B
$22.5K 0.01%
45
– –
SO icon
102
Southern Company
SO
$106B
$22.4K 0.01%
236
– –
CEG icon
103
Constellation Energy
CEG
$98.7B
$22K 0.01%
67
– –
VRTX icon
104
Vertex Pharmaceuticals
VRTX
$133B
$21.5K 0.01%
55
– –
DASH icon
105
DoorDash
DASH
$92.1B
$21.5K 0.01%
79
+6
+8% +$1.5K
MRSH
106
Marsh
MRSH
$90.1B
$21.4K 0.01%
106
– –
MCK icon
107
McKesson
MCK
$102B
$20.9K 0.01%
27
– –
CME icon
108
CME Group
CME
$94.3B
$20.8K 0.01%
77
– –
SBUX icon
109
Starbucks
SBUX
$124B
$20.7K 0.01%
245
– –
CDNS icon
110
Cadence Design Systems
CDNS
$89B
$20.7K 0.01%
59
– –
ICE icon
111
Intercontinental Exchange
ICE
$85B
$20.7K 0.01%
123
-1
-0.8% -$179
DUK icon
112
Duke Energy
DUK
$96.3B
$20.7K 0.01%
167
– –
CVS icon
113
CVS Health
CVS
$121B
$20.5K 0.01%
272
– –
PH icon
114
Parker-Hannifin
PH
$135B
$20.5K 0.01%
27
– –
TT icon
115
Trane Technologies
TT
$105B
$20.3K 0.01%
48
– –
NEM icon
116
Newmont
NEM
$124B
$19.9K 0.01%
236
-10
-4% -$697
BMY icon
117
Bristol-Myers Squibb
BMY
$130B
$19.8K 0.01%
438
– –
ORLY icon
118
O'Reilly Automotive
ORLY
$74.5B
$19.7K 0.01%
183
-3
-2% -$302
SNPS icon
119
Synopsys
SNPS
$79B
$19.2K 0.01%
39
+6
+18% +$3.39K
AMT icon
120
American Tower
AMT
$79.4B
$19.2K 0.01%
100
– –
KKR icon
121
KKR & Co
KKR
$99.5B
$19.1K 0.01%
147
+2
+1% +$284
GD icon
122
General Dynamics
GD
$107B
$18.4K 0.01%
54
– –
MMM icon
123
3M
MMM
$94.8B
$17.8K 0.01%
115
-2
-2% -$308
NKE icon
124
Nike
NKE
$60.1B
$17.8K 0.01%
255
– –
NOC icon
125
Northrop Grumman
NOC
$82B
$17.7K 0.01%
29
– –
3 4
5
6 7

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
ACM
Alight Capital Management New York $417M AUM 98.18% 1-Year Est. Return
MCM
Millstreet Capital Management Boston, Massachusetts $418M AUM 80.77% 1-Year Est. Return
MIA
Milestone Investment Advisors Middleton, Wisconsin $414M AUM 12.76% 1-Year Est. Return
SP
Sequent Planning Omaha, Nebraska $414M AUM 14.63% 1-Year Est. Return
SWC
Square Wave Capital Brooklyn, New York $413M AUM 15.36% 1-Year Est. Return
VIS
Vega Investment Solutions Paris, France $418M AUM

Howard Hughes Medical Institute's Q3 2025 Portfolio in Review

As of Q3 2025, Howard Hughes Medical Institute held 509 positions worth $171M, down 32% from $251M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Howard Hughes Medical Institute withdrew a net $96.1M in Q3 2025, closing 9 positions and reducing 141 holdings. Its most notable exit was Hess, an estimated $8.17K position sold in full.

By sector, the portfolio is most concentrated in Technology at 2.6% of assets, up from 1.6% a quarter earlier, followed by Financials and Consumer Discretionary.

Against the trend, Howard Hughes Medical Institute opened a new position in Applovin worth $41.7K.

  • Howard Hughes Medical Institute's largest Q3 2025 buy was Applovin: 58 shares worth $41.7K.
  • Howard Hughes Medical Institute added most to Amazon in Q3 2025, an estimated $10.2K increase.
  • Howard Hughes Medical Institute's biggest Q3 2025 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $96.2M.
  • Howard Hughes Medical Institute fully exited Hess in Q3 2025, selling an estimated $8.17K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $171M portfolio in Q3 2025.
  • Howard Hughes Medical Institute opened 8 new positions and closed 9 in Q3 2025.
  • Howard Hughes Medical Institute's portfolio value fell 32% quarter-over-quarter to $171M.

Based on Howard Hughes Medical Institute's 13F filing for Q3 2025, filed 14 Nov 2025.