We are live on ! Find out more
HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+7.99%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$171M
AUM Growth
-$80.3M
Cap. Flow
-$96.1M
Cap. Flow %
-56.34%
Top 10 Hldgs %
95.55%
Holding
509
New
8
Increased
62
Reduced
141
Closed
9

Top Buys

Rank Stock Value
1
APP icon
Applovin
APP
+$26.7K
2
HOOD icon
Robinhood
HOOD
+$18.1K
3
AMZN icon
Amazon
AMZN
+$10.2K
4
DDOG icon
Datadog
DDOG
+$9.5K
5
XYZ
Block Inc
XYZ
+$8.91K

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$96.2M
2
AAPL icon
Apple
AAPL
+$9.94K
3
HES
Hess
HES
+$8.17K
4
NVDA icon
NVIDIA
NVDA
+$7.84K
5
MSFT icon
Microsoft
MSFT
+$7.14K

Sector Composition

Rank Sector Weight
1 Technology 2.56%
2 Financials 0.95%
3 Consumer Discretionary 0.76%
4 Communication Services 0.75%
5 Healthcare 0.64%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CAG icon
476
Conagra Brands
CAG
$7.28B
$1.89K ﹤0.01%
103
– –
ALGN icon
477
Align Technology
ALGN
$12.3B
$1.88K ﹤0.01%
15
– –
APA icon
478
APA Corp
APA
$13.9B
$1.87K ﹤0.01%
77
-2
-3% -$42
MTCH icon
479
Match Group
MTCH
$8.39B
$1.84K ﹤0.01%
52
-2
-4% -$71
AOS icon
480
A.O. Smith
AOS
$8.46B
$1.83K ﹤0.01%
25
– –
EPAM icon
481
EPAM Systems
EPAM
$5.16B
$1.81K ﹤0.01%
12
– –
LW icon
482
Lamb Weston
LW
$7.32B
$1.74K ﹤0.01%
30
– –
CRL icon
483
Charles River Laboratories
CRL
$13.4B
$1.72K ﹤0.01%
11
– –
LKQ icon
484
LKQ Corp
LKQ
$6.24B
$1.71K ﹤0.01%
56
– –
TAP icon
485
Molson Coors Class B
TAP
$7.84B
$1.67K ﹤0.01%
37
– –
FRT icon
486
Federal Realty Investment Trust
FRT
$10.3B
$1.62K ﹤0.01%
16
– –
FOX icon
487
Fox Class B
FOX
$23.7B
$1.6K ﹤0.01%
28
– –
ERIE icon
488
Erie Indemnity
ERIE
$13.6B
$1.59K ﹤0.01%
5
– –
HRL icon
489
Hormel Foods
HRL
$13.5B
$1.53K ﹤0.01%
62
– –
BEN icon
490
Franklin Resources
BEN
$17.2B
$1.53K ﹤0.01%
66
– –
HSIC icon
491
Henry Schein
HSIC
$10.1B
$1.53K ﹤0.01%
23
-3
-12% -$208
MGM icon
492
MGM Resorts International
MGM
$11B
$1.52K ﹤0.01%
44
-4
-8% -$147
EMN icon
493
Eastman Chemical
EMN
$8.31B
$1.51K ﹤0.01%
24
– –
KMX icon
494
CarMax
KMX
$8.31B
$1.48K ﹤0.01%
33
– –
MHK icon
495
Mohawk Industries
MHK
$9.33B
$1.42K ﹤0.01%
11
– –
CPB icon
496
Campbell Soup
CPB
$6.85B
$1.33K ﹤0.01%
42
– –
PSKY
497
Paramount Skydance Corp
PSKY
$10.8B
$1.27K ﹤0.01%
+67
New +$1.06K
DVA icon
498
DaVita
DVA
$11.6B
$1.06K ﹤0.01%
8
-1
-11% -$137
BF.B icon
499
Brown-Forman Class B
BF.B
$13B
$1.03K ﹤0.01%
38
-1
-3% -$29
NWS icon
500
News Corp Class B
NWS
$17.7B
$829 ﹤0.01%
24
– –
17 18 19
20
21

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
ACM
Alight Capital Management New York $417M AUM 98.18% 1-Year Est. Return
MCM
Millstreet Capital Management Boston, Massachusetts $418M AUM 80.77% 1-Year Est. Return
MIA
Milestone Investment Advisors Middleton, Wisconsin $414M AUM 12.76% 1-Year Est. Return
SP
Sequent Planning Omaha, Nebraska $414M AUM 14.63% 1-Year Est. Return
SWC
Square Wave Capital Brooklyn, New York $413M AUM 15.36% 1-Year Est. Return
VIS
Vega Investment Solutions Paris, France $418M AUM

Howard Hughes Medical Institute's Q3 2025 Portfolio in Review

As of Q3 2025, Howard Hughes Medical Institute held 509 positions worth $171M, down 32% from $251M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Howard Hughes Medical Institute withdrew a net $96.1M in Q3 2025, closing 9 positions and reducing 141 holdings. Its most notable exit was Hess, an estimated $8.17K position sold in full.

By sector, the portfolio is most concentrated in Technology at 2.6% of assets, up from 1.6% a quarter earlier, followed by Financials and Consumer Discretionary.

Against the trend, Howard Hughes Medical Institute opened a new position in Applovin worth $41.7K.

  • Howard Hughes Medical Institute's largest Q3 2025 buy was Applovin: 58 shares worth $41.7K.
  • Howard Hughes Medical Institute added most to Amazon in Q3 2025, an estimated $10.2K increase.
  • Howard Hughes Medical Institute's biggest Q3 2025 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $96.2M.
  • Howard Hughes Medical Institute fully exited Hess in Q3 2025, selling an estimated $8.17K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $171M portfolio in Q3 2025.
  • Howard Hughes Medical Institute opened 8 new positions and closed 9 in Q3 2025.
  • Howard Hughes Medical Institute's portfolio value fell 32% quarter-over-quarter to $171M.

Based on Howard Hughes Medical Institute's 13F filing for Q3 2025, filed 14 Nov 2025.