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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
476
Molson Coors Class B
TAP
$7.75B
| $1.78K | ﹤0.01% |
+37
| New | +$2.04K |
|
|
WBA
477
DELISTED
Walgreens Boots Alliance
WBA
| $1.78K | ﹤0.01% |
+155
| New | +$1.73K |
|
478
Bio-Techne
TECH
$11.3B
| $1.75K | ﹤0.01% |
+34
| New | +$1.71K |
|
479
Erie Indemnity
ERIE
$13.5B
| $1.73K | ﹤0.01% |
+5
| New | +$1.85K |
|
480
Generac Holdings
GNRC
$13.1B
| $1.72K | ﹤0.01% |
+12
| New | +$1.46K |
|
481
Charles River Laboratories
CRL
$13.6B
| $1.67K | ﹤0.01% |
+11
| New | +$1.47K |
|
482
Match Group
MTCH
$8.4B
| $1.67K | ﹤0.01% |
+54
| New | +$1.61K |
|
483
MGM Resorts International
MGM
$11.1B
| $1.65K | ﹤0.01% |
+48
| New | +$1.52K |
|
|
PARA
484
DELISTED
Paramount Global Class B
PARA
| $1.65K | ﹤0.01% |
+128
| New | +$1.5K |
|
485
A.O. Smith
AOS
$8.51B
| $1.64K | ﹤0.01% |
+25
| New | +$1.64K |
|
486
AES
AES
$10.5B
| $1.61K | ﹤0.01% |
+153
| New | +$1.64K |
|
487
Franklin Resources
BEN
$17.1B
| $1.57K | ﹤0.01% |
+66
| New | +$1.36K |
|
488
Albemarle
ALB
$15.1B
| $1.57K | ﹤0.01% |
+25
| New | +$1.48K |
|
489
Lamb Weston
LW
$7.3B
| $1.56K | ﹤0.01% |
+30
| New | +$1.61K |
|
490
Federal Realty Investment Trust
FRT
$10.2B
| $1.52K | ﹤0.01% |
+16
| New | +$1.51K |
|
491
Invesco
IVZ
$13.9B
| $1.51K | ﹤0.01% |
+96
| New | +$1.38K |
|
492
Fox Class B
FOX
$23.5B
| $1.45K | ﹤0.01% |
+28
| New | +$1.36K |
|
493
APA Corp
APA
$14B
| $1.45K | ﹤0.01% |
+79
| New | +$1.37K |
|
494
Campbell Soup
CPB
$6.74B
| $1.29K | ﹤0.01% |
+42
| New | +$1.48K |
|
495
DaVita
DVA
$11.6B
| $1.28K | ﹤0.01% |
+9
| New | +$1.27K |
|
496
Caesars Entertainment
CZR
$6.04B
| $1.28K | ﹤0.01% |
+45
| New | +$1.22K |
|
|
RAL
497
Ralliant Corp
RAL
$8.03B
| $1.16K | ﹤0.01% |
+24
| New | +$1.18K |
|
498
Mohawk Industries
MHK
$9.27B
| $1.15K | ﹤0.01% |
+11
| New | +$1.15K |
|
499
Enphase Energy
ENPH
$5.39B
| $1.11K | ﹤0.01% |
+28
| New | +$1.29K |
|
500
Brown-Forman Class B
BF.B
$12.8B
| $1.05K | ﹤0.01% |
+39
| New | +$1.25K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.