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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
WELL icon
476
Welltower
WELL
$169B
– –
-147
Closed -$27.3K
WFC icon
477
Wells Fargo
WFC
$261B
– –
-677
Closed -$63.1K
WMB icon
478
Williams Companies
WMB
$87.5B
– –
-263
Closed -$15.8K
WM icon
479
Waste Management
WM
$90.6B
– –
-79
Closed -$17.4K
WMT icon
480
Walmart Inc
WMT
$885B
– –
-947
Closed -$106K
WRB icon
481
W.R. Berkley
WRB
$26.9B
– –
-64
Closed -$4.49K
WSM icon
482
Williams-Sonoma
WSM
$26.9B
– –
-26
Closed -$4.64K
WST icon
483
West Pharmaceutical
WST
$24B
– –
-15
Closed -$4.13K
WTW icon
484
Willis Towers Watson
WTW
$31.7B
– –
-21
Closed -$6.9K
WYNN icon
485
Wynn Resorts
WYNN
$10.3B
– –
-19
Closed -$2.29K
WY icon
486
Weyerhaeuser
WY
$18B
– –
-155
Closed -$3.67K
XEL icon
487
Xcel Energy
XEL
$48.8B
– –
-127
Closed -$9.38K
XOM icon
488
ExxonMobil
XOM
$644B
– –
-912
Closed -$110K
XYL icon
489
Xylem
XYL
$27.3B
– –
-52
Closed -$7.08K
YUM icon
490
Yum! Brands
YUM
$42.2B
– –
-60
Closed -$9.08K
ZBH icon
491
Zimmer Biomet
ZBH
$18.2B
– –
-43
Closed -$3.87K
ZBRA icon
492
Zebra Technologies
ZBRA
$14B
– –
-11
Closed -$2.67K
ZTS icon
493
Zoetis
ZTS
$32.4B
– –
-95
Closed -$12K
DAY
494
DELISTED
Dayforce
DAY
– –
-34
Closed -$2.35K
CPAY icon
495
Corpay
CPAY
$25B
– –
-15
Closed -$4.51K
SOLV icon
496
Solventum
SOLV
$14.8B
– –
-31
Closed -$2.46K
GEV icon
497
GE Vernova
GEV
$264B
– –
-59
Closed -$38.6K
SW
498
Smurfit Westrock
SW
$24.1B
– –
-112
Closed -$4.33K
EXE
499
Expand Energy Corp
EXE
$21.8B
– –
-51
Closed -$5.63K
XYZ
500
Block Inc
XYZ
$48.4B
– –
-118
Closed -$7.68K
17 18 19
20
21

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VM
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SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
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SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
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Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.