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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
UHS icon
451
Universal Health Services
UHS
$10.2B
– –
-12
Closed -$2.62K
ULTA icon
452
Ulta Beauty
ULTA
$22B
– –
-10
Closed -$6.05K
UNH icon
453
UnitedHealth
UNH
$376B
– –
-195
Closed -$64.4K
UNP icon
454
Union Pacific
UNP
$174B
– –
-128
Closed -$29.6K
UPS icon
455
United Parcel Service
UPS
$88.6B
– –
-159
Closed -$15.8K
URI icon
456
United Rentals
URI
$67.2B
– –
-14
Closed -$11.3K
USB icon
457
US Bancorp
USB
$98.2B
– –
-335
Closed -$17.9K
V icon
458
Visa
V
$684B
– –
-364
Closed -$128K
VICI icon
459
VICI Properties
VICI
$29B
– –
-230
Closed -$6.47K
VLO icon
460
Valero Energy
VLO
$90.1B
– –
-66
Closed -$10.7K
VLTO icon
461
Veralto
VLTO
$23B
– –
-53
Closed -$5.29K
VMC icon
462
Vulcan Materials
VMC
$34.8B
– –
-28
Closed -$7.99K
VRSK icon
463
Verisk Analytics
VRSK
$25.4B
– –
-30
Closed -$6.71K
VRSN icon
464
VeriSign
VRSN
$26.2B
– –
-18
Closed -$4.37K
VRTX icon
465
Vertex Pharmaceuticals
VRTX
$121B
– –
-55
Closed -$24.9K
VST icon
466
Vistra
VST
$50B
– –
-69
Closed -$11.1K
VTR icon
467
Ventas
VTR
$48B
– –
-101
Closed -$7.82K
VTRS icon
468
Viatris
VTRS
$20.4B
– –
-376
Closed -$4.68K
VZ icon
469
Verizon
VZ
$195B
– –
-908
Closed -$37K
WAB icon
470
Wabtec
WAB
$49.1B
– –
-36
Closed -$7.68K
WAT icon
471
Waters Corp
WAT
$37B
– –
-12
Closed -$4.56K
WBD icon
472
Warner Bros
WBD
$65.9B
– –
-531
Closed -$15.3K
WDAY icon
473
Workday
WDAY
$39.6B
– –
-46
Closed -$9.88K
WDC icon
474
Western Digital
WDC
$188B
– –
-74
Closed -$12.7K
WEC icon
475
WEC Energy
WEC
$35.7B
– –
-70
Closed -$7.38K
17 18
19
20 21

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VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.