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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PG icon
26
Procter & Gamble
PG
$335B
$72.2K 0.04%
504
– –
GE icon
27
GE Aerospace
GE
$379B
$70.2K 0.04%
228
– –
ORCL icon
28
Oracle
ORCL
$442B
$70.2K 0.04%
360
+5
+1% +$1.19K
MU icon
29
Micron Technology
MU
$1.03T
$68.8K 0.04%
241
+1
+0.4% +$229
CSCO icon
30
Cisco
CSCO
$488B
$65.5K 0.04%
850
-1
-0.1% -$74
UNH icon
31
UnitedHealth
UNH
$364B
$64.4K 0.04%
195
– –
WFC icon
32
Wells Fargo
WFC
$269B
$63.1K 0.04%
677
-11
-2% -$955
CVX icon
33
Chevron
CVX
$386B
$62.3K 0.04%
409
-5
-1% -$762
IBM icon
34
IBM
IBM
$222B
$59.5K 0.03%
201
+1
+0.5% +$299
KO icon
35
Coca-Cola
KO
$373B
$58.4K 0.03%
835
+3
+0.4% +$209
CAT icon
36
Caterpillar
CAT
$393B
$57.9K 0.03%
101
– –
GS icon
37
Goldman Sachs
GS
$302B
$57.1K 0.03%
65
-1
-2% -$816
MRK icon
38
Merck
MRK
$328B
$56.2K 0.03%
534
-3
-0.6% -$282
CRM icon
39
Salesforce
CRM
$158B
$54.3K 0.03%
205
-1
-0.5% -$249
RTX icon
40
RTX Corp
RTX
$300B
$52.8K 0.03%
288
+1
+0.3% +$174
MCD icon
41
McDonald's
MCD
$195B
$47.1K 0.03%
154
– –
ABT icon
42
Abbott
ABT
$192B
$47K 0.03%
375
+1
+0.3% +$127
TMO icon
43
Thermo Fisher Scientific
TMO
$223B
$46.9K 0.03%
81
-1
-1% -$566
MS icon
44
Morgan Stanley
MS
$342B
$46.3K 0.03%
261
– –
LRCX icon
45
Lam Research
LRCX
$408B
$46.2K 0.03%
270
-2
-0.7% -$311
C icon
46
Citigroup
C
$231B
$45K 0.03%
386
-10
-3% -$1.04K
AMAT icon
47
Applied Materials
AMAT
$435B
$44.2K 0.03%
172
-1
-0.6% -$240
DIS icon
48
Walt Disney
DIS
$178B
$43.8K 0.03%
385
-2
-0.5% -$220
ISRG icon
49
Intuitive Surgical
ISRG
$142B
$43.6K 0.03%
77
– –
LIN icon
50
Linde
LIN
$221B
$43.1K 0.02%
101
– –
1
2
3 4 5

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ACM
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MCM
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MIA
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SP
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SWC
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VIS
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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.