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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BLDR icon
451
Builders FirstSource
BLDR
$7.79B
$2.47K ﹤0.01%
24
– –
EPAM icon
452
EPAM Systems
EPAM
$5.17B
$2.46K ﹤0.01%
12
– –
SOLV icon
453
Solventum
SOLV
$14.5B
$2.46K ﹤0.01%
31
– –
SWK icon
454
Stanley Black & Decker
SWK
$15.5B
$2.45K ﹤0.01%
33
– –
HST icon
455
Host Hotels & Resorts
HST
$15.6B
$2.45K ﹤0.01%
138
– –
LYB icon
456
LyondellBasell Industries
LYB
$20.3B
$2.42K ﹤0.01%
56
– –
RVTY icon
457
Revvity
RVTY
$13.2B
$2.42K ﹤0.01%
25
– –
REG icon
458
Regency Centers
REG
$13.9B
$2.42K ﹤0.01%
35
– –
DOC icon
459
Healthpeak Properties
DOC
$14.2B
$2.41K ﹤0.01%
150
– –
UDR icon
460
UDR
UDR
$12B
$2.38K ﹤0.01%
65
– –
DAY
461
DELISTED
Dayforce
DAY
$2.35K ﹤0.01%
34
– –
ALGN icon
462
Align Technology
ALGN
$12.4B
$2.34K ﹤0.01%
15
– –
FDS icon
463
Factset
FDS
$9.89B
$2.32K ﹤0.01%
8
– –
HAS icon
464
Hasbro
HAS
$13.4B
$2.3K ﹤0.01%
28
– –
WYNN icon
465
Wynn Resorts
WYNN
$10.6B
$2.29K ﹤0.01%
19
– –
PNW icon
466
Pinnacle West Capital
PNW
$12.2B
$2.22K ﹤0.01%
25
– –
MRNA icon
467
Moderna
MRNA
$25.4B
$2.21K ﹤0.01%
75
+1
+1% +$27
AES icon
468
AES
AES
$10.5B
$2.19K ﹤0.01%
153
– –
CRL icon
469
Charles River Laboratories
CRL
$13.6B
$2.19K ﹤0.01%
11
– –
NCLH icon
470
Norwegian Cruise Line
NCLH
$8.69B
$2.19K ﹤0.01%
98
+1
+1% +$21
SJM icon
471
J.M. Smucker
SJM
$12.7B
$2.15K ﹤0.01%
22
– –
NWSA icon
472
News Corp Class A
NWSA
$15.5B
$2.12K ﹤0.01%
81
– –
BAX icon
473
Baxter International
BAX
$13.9B
$2.1K ﹤0.01%
110
– –
BXP icon
474
Boston Properties
BXP
$10.8B
$2.09K ﹤0.01%
31
– –
SWKS icon
475
Skyworks Solutions
SWKS
$10.5B
$2.03K ﹤0.01%
32
– –
17 18
19
20 21

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SSC
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ACM
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MCM
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MIA
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SP
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SWC
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VIS
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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.