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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+7.99%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$171M
AUM Growth
-$80.3M
Cap. Flow
-$96.1M
Cap. Flow %
-56.34%
Top 10 Hldgs %
95.55%
Holding
509
New
8
Increased
62
Reduced
141
Closed
9

Top Buys

Rank Stock Value
1
APP icon
Applovin
APP
+$26.7K
2
HOOD icon
Robinhood
HOOD
+$18.1K
3
AMZN icon
Amazon
AMZN
+$10.2K
4
DDOG icon
Datadog
DDOG
+$9.5K
5
XYZ
Block Inc
XYZ
+$8.91K

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$96.2M
2
AAPL icon
Apple
AAPL
+$9.94K
3
HES
Hess
HES
+$8.17K
4
NVDA icon
NVIDIA
NVDA
+$7.84K
5
MSFT icon
Microsoft
MSFT
+$7.14K

Sector Composition

Rank Sector Weight
1 Technology 2.56%
2 Financials 0.95%
3 Consumer Discretionary 0.76%
4 Communication Services 0.75%
5 Healthcare 0.64%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DPZ icon
426
Domino's
DPZ
$11.7B
$3.02K ﹤0.01%
7
– –
BALL icon
427
Ball Corp
BALL
$16.4B
$2.98K ﹤0.01%
59
-5
-8% -$270
COO icon
428
Cooper Companies
COO
$15B
$2.95K ﹤0.01%
43
– –
BLDR icon
429
Builders FirstSource
BLDR
$7.79B
$2.91K ﹤0.01%
24
– –
FOXA icon
430
Fox Class A
FOXA
$26.5B
$2.9K ﹤0.01%
46
-1
-2% -$58
DOC icon
431
Healthpeak Properties
DOC
$14.2B
$2.87K ﹤0.01%
150
-1
-0.7% -$18
TKO icon
432
TKO Group
TKO
$14.3B
$2.83K ﹤0.01%
14
– –
AVY icon
433
Avery Dennison
AVY
$13.7B
$2.76K ﹤0.01%
17
– –
ARE icon
434
Alexandria Real Estate Equities
ARE
$8.27B
$2.75K ﹤0.01%
33
– –
LYB icon
435
LyondellBasell Industries
LYB
$20.3B
$2.75K ﹤0.01%
56
– –
IEX icon
436
IDEX
IEX
$17.7B
$2.6K ﹤0.01%
16
– –
GL icon
437
Globe Life
GL
$13.8B
$2.57K ﹤0.01%
18
– –
REG icon
438
Regency Centers
REG
$13.9B
$2.55K ﹤0.01%
35
– –
RL icon
439
Ralph Lauren
RL
$23.6B
$2.51K ﹤0.01%
8
– –
BAX icon
440
Baxter International
BAX
$13.9B
$2.5K ﹤0.01%
110
– –
NDSN icon
441
Nordson
NDSN
$17.3B
$2.5K ﹤0.01%
11
– –
NWSA icon
442
News Corp Class A
NWSA
$15.5B
$2.49K ﹤0.01%
81
– –
POOL icon
443
Pool Corp
POOL
$7.25B
$2.48K ﹤0.01%
8
– –
SWKS icon
444
Skyworks Solutions
SWKS
$10.5B
$2.46K ﹤0.01%
32
-2
-6% -$149
CPT icon
445
Camden Property Trust
CPT
$10.9B
$2.46K ﹤0.01%
23
– –
SWK icon
446
Stanley Black & Decker
SWK
$15.5B
$2.45K ﹤0.01%
33
– –
UHS icon
447
Universal Health Services
UHS
$10.2B
$2.45K ﹤0.01%
12
– –
BG icon
448
Bunge Global
BG
$21.5B
$2.44K ﹤0.01%
30
+2
+7% +$160
WYNN icon
449
Wynn Resorts
WYNN
$10.6B
$2.44K ﹤0.01%
19
– –
UDR icon
450
UDR
UDR
$12B
$2.42K ﹤0.01%
65
– –
16 17
18
19 20

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ACM
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MCM
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MIA
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SP
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SWC
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VIS
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Howard Hughes Medical Institute's Q3 2025 Portfolio in Review

As of Q3 2025, Howard Hughes Medical Institute held 509 positions worth $171M, down 32% from $251M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Howard Hughes Medical Institute withdrew a net $96.1M in Q3 2025, closing 9 positions and reducing 141 holdings. Its most notable exit was Hess, an estimated $8.17K position sold in full.

By sector, the portfolio is most concentrated in Technology at 2.6% of assets, up from 1.6% a quarter earlier, followed by Financials and Consumer Discretionary.

Against the trend, Howard Hughes Medical Institute opened a new position in Applovin worth $41.7K.

  • Howard Hughes Medical Institute's largest Q3 2025 buy was Applovin: 58 shares worth $41.7K.
  • Howard Hughes Medical Institute added most to Amazon in Q3 2025, an estimated $10.2K increase.
  • Howard Hughes Medical Institute's biggest Q3 2025 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $96.2M.
  • Howard Hughes Medical Institute fully exited Hess in Q3 2025, selling an estimated $8.17K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $171M portfolio in Q3 2025.
  • Howard Hughes Medical Institute opened 8 new positions and closed 9 in Q3 2025.
  • Howard Hughes Medical Institute's portfolio value fell 32% quarter-over-quarter to $171M.

Based on Howard Hughes Medical Institute's 13F filing for Q3 2025, filed 14 Nov 2025.