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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
Cap. Flow
+$25.5M
Cap. Flow %
10.17%
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1

Top Buys

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$15.6M
2
MSFT icon
Microsoft
MSFT
+$700K
3
NVDA icon
NVIDIA
NVDA
+$665K
4
AAPL icon
Apple
AAPL
+$653K
5
AMZN icon
Amazon
AMZN
+$403K

Top Sells

Rank Stock Value
1
BIOA
BioAge Labs
BIOA
+$428K

Sector Composition

Rank Sector Weight
1 Technology 1.55%
2 Financials 0.62%
3 Consumer Discretionary 0.47%
4 Communication Services 0.44%
5 Healthcare 0.42%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
JNPR
426
DELISTED
Juniper Networks
JNPR
$2.83K ﹤0.01%
+71
New +$2.54K
BBY icon
427
Best Buy
BBY
$17.5B
$2.82K ﹤0.01%
+42
New +$2.85K
IEX icon
428
IDEX
IEX
$17.7B
$2.81K ﹤0.01%
+16
New +$2.84K
BLDR icon
429
Builders FirstSource
BLDR
$7.79B
$2.8K ﹤0.01%
+24
New +$2.77K
JKHY icon
430
Jack Henry & Associates
JKHY
$10.8B
$2.7K ﹤0.01%
+15
New +$2.66K
UDR icon
431
UDR
UDR
$12B
$2.65K ﹤0.01%
+65
New +$2.69K
DOC icon
432
Healthpeak Properties
DOC
$14.2B
$2.64K ﹤0.01%
+151
New +$2.68K
FOXA icon
433
Fox Class A
FOXA
$26.5B
$2.63K ﹤0.01%
+47
New +$2.48K
ALLE icon
434
Allegion
ALLE
$14.1B
$2.59K ﹤0.01%
+18
New +$2.46K
CPT icon
435
Camden Property Trust
CPT
$10.9B
$2.59K ﹤0.01%
+23
New +$2.65K
VTRS icon
436
Viatris
VTRS
$18.5B
$2.58K ﹤0.01%
+289
New +$2.44K
AKAM icon
437
Akamai
AKAM
$17.6B
$2.55K ﹤0.01%
+32
New +$2.49K
TKO icon
438
TKO Group
TKO
$14.3B
$2.55K ﹤0.01%
+14
New +$2.25K
SWKS icon
439
Skyworks Solutions
SWKS
$10.5B
$2.53K ﹤0.01%
+34
New +$2.27K
RVTY icon
440
Revvity
RVTY
$13.2B
$2.52K ﹤0.01%
+26
New +$2.45K
REG icon
441
Regency Centers
REG
$13.9B
$2.49K ﹤0.01%
+35
New +$2.5K
MOS icon
442
The Mosaic Company
MOS
$7.18B
$2.48K ﹤0.01%
+68
New +$2.18K
JBHT icon
443
JB Hunt Transport Services
JBHT
$25.9B
$2.44K ﹤0.01%
+17
New +$2.35K
NWSA icon
444
News Corp Class A
NWSA
$15.5B
$2.41K ﹤0.01%
+81
New +$2.23K
CHRW icon
445
C.H. Robinson
CHRW
$17.1B
$2.4K ﹤0.01%
+25
New +$2.34K
ARE icon
446
Alexandria Real Estate Equities
ARE
$8.27B
$2.4K ﹤0.01%
+33
New +$2.45K
NDSN icon
447
Nordson
NDSN
$17.3B
$2.36K ﹤0.01%
+11
New +$2.19K
POOL icon
448
Pool Corp
POOL
$7.25B
$2.33K ﹤0.01%
+8
New +$2.42K
HST icon
449
Host Hotels & Resorts
HST
$15.6B
$2.32K ﹤0.01%
+151
New +$2.24K
PAYC icon
450
Paycom
PAYC
$9.52B
$2.31K ﹤0.01%
+10
New +$2.37K
16 17
18
19 20

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ACM
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MCM
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MIA
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SP
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VIS
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review

As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.

Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.

By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.

On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.

  • Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
  • Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
  • Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
  • Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
  • Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
  • Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.

Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.