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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
STZ icon
376
Constellation Brands
STZ
$22.9B
$4.28K ﹤0.01%
31
– –
PODD icon
377
Insulet
PODD
$10.1B
$4.26K ﹤0.01%
15
– –
DGX icon
378
Quest Diagnostics
DGX
$26.2B
$4.17K ﹤0.01%
24
– –
CNC icon
379
Centene
CNC
$33.1B
$4.16K ﹤0.01%
101
– –
KEY icon
380
KeyCorp
KEY
$24.5B
$4.15K ﹤0.01%
201
– –
AMCR icon
381
Amcor
AMCR
$21.5B
$4.14K ﹤0.01%
99
– –
WST icon
382
West Pharmaceutical
WST
$24.8B
$4.13K ﹤0.01%
15
– –
TYL icon
383
Tyler Technologies
TYL
$13B
$4.09K ﹤0.01%
9
– –
TRMB icon
384
Trimble
TRMB
$13.1B
$4.07K ﹤0.01%
52
– –
IT icon
385
Gartner
IT
$11.3B
$4.04K ﹤0.01%
16
– –
CHRW icon
386
C.H. Robinson
CHRW
$17.1B
$4.02K ﹤0.01%
25
– –
CHTR icon
387
Charter Communications
CHTR
$17.9B
$3.97K ﹤0.01%
19
-1
-5% -$225
GPN icon
388
Global Payments
GPN
$23.4B
$3.95K ﹤0.01%
51
-2
-4% -$161
PKG icon
389
Packaging Corp of America
PKG
$22.8B
$3.92K ﹤0.01%
19
– –
L icon
390
Loews
L
$23.1B
$3.9K ﹤0.01%
37
– –
PFG icon
391
Principal Financial Group
PFG
$24.4B
$3.88K ﹤0.01%
44
– –
ZBH icon
392
Zimmer Biomet
ZBH
$18.7B
$3.87K ﹤0.01%
43
– –
CDW icon
393
CDW
CDW
$17.1B
$3.81K ﹤0.01%
28
– –
FTV icon
394
Fortive
FTV
$18.6B
$3.81K ﹤0.01%
69
-4
-5% -$208
SNA icon
395
Snap-on
SNA
$21.1B
$3.79K ﹤0.01%
11
– –
ROL icon
396
Rollins
ROL
$17.6B
$3.78K ﹤0.01%
63
+3
+5% +$176
GDDY icon
397
GoDaddy
GDDY
$11.6B
$3.72K ﹤0.01%
30
– –
IFF icon
398
International Flavors & Fragrances
IFF
$21.4B
$3.71K ﹤0.01%
55
– –
GPC icon
399
Genuine Parts
GPC
$18.5B
$3.69K ﹤0.01%
30
– –
MKC icon
400
McCormick & Company Non-Voting
MKC
$14.2B
$3.68K ﹤0.01%
54
– –
14 15
16
17 18

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SSC
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ACM
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MCM
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MIA
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SP
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SWC
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VIS
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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.